論文

• Eriko Nara, Hung Wei Lai, Hideo Imazato, Masahiro Ishizuka, Motowo Nakajima, Shun-Ichiro Ogura. Suppression of angiotensin converting enzyme 2, a host receptor for SARS-CoV-2 infection, using 5-aminolevulinic acid in vitro, Plos ONE, Vol. 18, No. 2, Feb. 2023.
• Hung Wei Lai, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Efficiency of aminolevulinic acid (ALA)-photodynamic therapy based on ALA uptake transporters in a cell density-dependent malignancy model, Journal of Photochemistry and Photobiology B: Biology, Vol. 218, May 2021.
• Taku Nakayama, Tatsuya Kobayashi, Otsuka Shinpei, Hideo Fukuhara, Tsutomu Namikawa, Keiji Inoue, Kazuhiro Hanazaki, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Photoirradiation after aminolevulinic acid treatment suppresses cancer cell proliferation through the HO-1/p21 pathway, Photodiagnosis and photodynamic therapy, Vol. 28, pp. 10-17, Dec. 2019.
• Hung Wei Lai, Ryuta Sasaki, Shiro Usuki, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Novel Strategy to Increase Specificity of ALA-Induced PpIX Accumulation through Inhibition of Transporters Involved in ALA Uptake, Photodiagnosis and photodynamic therapy, Vol. 27, pp. 327-335, June 2019.
• Yuta Sugiyama, Yukari Hiraiwa, Yuichiro Hagiya, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. 5-Aminolevulinic acid regulates the immune response in LPS-stimulated RAW 264.7 macrophages, BMC immunology, Vol. 19, pp. 41, Dec. 2018.
• Taku Nakayama, Shinpei Otsuka, Tatsuya Kobayashi, Hodaka Okajima, Kentaro Matsumoto, Yuichiro Hagiya, Keiji Inoue, Taro Shuin, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy, Scientific Reports, Vol. 6, No. 36478, Nov. 2016.
• Shinpei Otsuka, Kentaro Matsumoto, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Oxygen availability for porphyrin biosynthesis enzymes determines the production of protoporphyrin IX (PpIX) during hypoxia, PLOS ONE, 10, e0146026, Dec. 2015.
• Mai Miura, Kensuke Ito, Maiko Hayashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. The effect of 5-aminolevulinic acid on cytochrome P450-mediated prodrug activation, PLOS ONE, 10, e0131793, July 2015.
• Kentarou Matsumoto, Yuichiro Hagiya, Yoshio Endo, Motowo Nakajima, Masahiro Ishizuka, Tohru Tanaka, Shun-ichiro Ogura. Effects of plasma membrane ABCB6 on 5-aminolevulinic acid (ALA)-induced porphyrin accumulation in vitro: Tumor cell response to hypoxia, Photodiagnosis and Photodynamic Therapy, 12, 45-51, Mar. 2015.
• Maiko Hayashi, Hideo Fukuhara, Keiji Inoue, Taro Shuin, Yuichiro Hagiya, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. The effect of iron ion on the specificity of photodynamic therapy with 5-aminolevulinic acid, PLOS ONE, 10, e0122351, Mar. 2015.
• Taku Chibazakura, Yui Toriyabe, Hiroshi Fujii, Kiwamu Takahashi, Mariko Kawakami, Haruna Kuwamura, Hazuki Haga, Shun-ichiro OGURA, Fuminori Abe, Motowo Nakajima, Hirofumi Yoshikawa, Tohru Tanaka. 5-aminolevulinic acid enhances cell death under thermal stress in certain cancer cell lines, Bioscience Biotechnology and Biochemistry, 79, 422-431, Mar. 2015.

国際会議発表 (査読有り)

• Taku Nakayama, Shinpei Otsuka, Kazuhiro Hanazaki, Keiji Inoue, Taro Shuin, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Dormant Cancer Cells Accumulate High Protoporphyrin IX Levels And Are Sensitive To 5-aminolevulinic Acid-based Photodynamic Therapy, 17th International Photodynamic Association World Congress, June 2019.

国際会議発表 (査読なし・不明)

• Lai HW,  Yamamoto S, Takahashi K, Nakajima M, Hanazaki K, Inoue K, Ogura S. Novel strategy to increase specificity of aminolevulinic acid-photodynamic therapy in cancer, 5th International Conference on Molecular Biology & Biotechnology 2022, June 2022.
• Hung Wei Lai, Ryota Sasaki, Shiro Usuki, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Novel strategy to increase specificity of ALA-induced PpIX accumulation through inhibition of transporters involved in ALA uptake, The 7 th International ALA and Porphyrin Symposium, Dec. 2019.
• Arif Suprihadi, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. The effect of heme biosynthesis on the mitochondrial functions in C2C12 cell line, 17th International Photodynamic Association World Congress, June 2019.
• Hung Wei Lai, Ryota Sasaki, Shiro Usuki, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Novel strategy to increase specificity of ALA-induced PpIX accumulation through inhibition of transporters involved in ALA uptake, 17th International Photodynamic Association World Congress, June 2019.
• Arif Suprihadi, Lai Hung Wei, Tan Hui Sin, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. The Effect of Heme Biosynthesis on the Electron Transport Chain in C2C12 cell line, Nov. 2018.
• Taku Nakayama, Shimpei Otsuka, Kazuhiro Hanazaki, Keiji Inoue, Taro Shuin, Motowo Nakajima, Tohru Tanaka, Shun-ichiro Ogura. Dormant Cancer Cells Accumulate High Protoporphyrin IX Levels And Are Sensitive To 5-aminolevulinic Acid-based Photodynamic Therapy, 6th International ALA and Porphyrin Symposium, Oct. 2018.
• Shun-ichiro Ogura, Taku Nakayama, Keiji Inoue, Motowo Nakajima, Tohru Tanaka. Applications of Aminolevulinic acid in tumor – From Diagnosis and Therapy to Screening, Photodynamic Therapy and Photodiagnosis Update 2018, Sept. 2018.
• Shun-ichiro Ogura, Keiji Inoue, Hideo Fukuhara, Motowo Nakajima, Tohru Tanaka. Porphyrins as urinary biomarkers for bladder cancer after 5-aminolevulinic acid administration: The potential of photodynamic screening for tumors, The 5th International ALA and Porphyrin Symposium, Dec. 2017.

国内会議発表 (査読なし・不明)

• Nakayama T, Takahashi K, Nakajima M, Inoue K, Ogura S. Mitomycin C-induced cell cycle arrest enhances 5-aminolevulinic acid-based photodynamic therapy for bladder cancer, 第79回日本癌学会学術総会, Oct. 2020.
• Lai Hung Wei, Hagiya Yuichiro, Nakajima Motowo, Ogura Shun-ichiro. Comparison of various human amino acid transporters in enhancing cellular aminolevulinic acid (ALA) uptake in prostate cancer cells in vitro, 第8回ポルフィリン-ALA学会年会, Apr. 2018.

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