論文

• Takako Ohyama, Takuo Osawa, Shun-ichi Sekine, Takako Ohyama, Takuo Osawa, Shun-ichi Sekine, Yoshitaka Ishii. NMR Studies of Genomic RNA in 3′ Untranslated Region Unveil Pseudoknot Structure that Initiates Viral RNA Replication in SARS-CoV-2, JACS Au, Mar. 2024.  公式リンク  
  
• Kousuke Kashihara, Muneki Oouchi, Yu Kodama, Tatsuhiro Arai, Miki Horie, Takehiro Kitaura, Yoshitaka Ishii. High-Field Nuclear Magnetic Resonance Studies Reveal New Structural Landscape of Sulfur-Vulcanized Natural Rubber, Biomacromolecules, Nov. 2022.  公式リンク  
  
• Tatsuya Matsunaga, Ryotaro Okabe, Yoshitaka Ishii. Efficient solvent suppression with adiabatic inversion for 1H-detected solid-state NMR, Journal of Biomolecular NMR, Oct. 2021.  公式リンク  
  
• Ayesha Wickramasinghe, Yiling Xiao, Naohiro Kobayashi, Songlin Wang, Kathryn P. Scherpelz, Toshio Yamazaki, Stephen C. Meredith, Yoshitaka Ishii. Sensitivity-Enhanced Solid-State NMR Detection of Structural Differences and Unique Polymorphs in Pico- to Nanomolar Amounts of Brain-Derived and Synthetic 42-Residue Amyloid-β Fibrils, Journal of the American Chemical Society, July 2021.  公式リンク  
  
• Kathryn P. Scherpelz, Songlin Wang, Peter Pytel, Rama S. Madhurapantula, Joseph R. Sachleben, Joseph Orgel3, Yoshitaka Ishii, Stephen C. Meredith. Atomic-level differences between brain parenchymal- and cerebrovascular-seeded Aβ fibrils, Scientific Reports, Vol. 11, No. 1, Jan. 2021.  公式リンク  
  
• Tatsuya Matsunaga, Isamu Matsuda, Toshio Yamazaki, Yoshitaka Ishii. Decoherence optimized tilted-angle cross polarization: A novel concept for sensitivity-enhanced solid-state NMR using ultra-fast magic angle spinning, Journal of Magnetic Resonance, Volume 322, pp. 106857, Nov. 2020.  公式リンク  
  
• Takako Ohyama, Hazuki Takahashi, Harshita Sharma, Toshio Yamazaki, Stefano Gustincich, Yoshitaka Ishii, Piero Carninci. An NMR-based approach reveals the core structure of the functional domain of SINEUP lncRNAs, Nucleic Acids Research, Sept. 2020.  公式リンク  
  
• Yiling Xiao, Isamu Matsuda, Masafumi Inoue, Tomoya Sasahara, Minako Hoshi, Yoshitaka Ishii. NMR-based site-resolved profiling of β-amyloid misfolding reveals structural transitions from pathologically relevant spherical oligomer to fibril, Journal of Biological Chemistry, Nov. 2019.  公式リンク  
  
• Yoshitaka Ishii. The MIRAI Program and the New Super-High Field NMR Initiative and Its Relevance to the Development of Superconducting Joints in Japan, IEEE Transactions on Applied Superconductivity, Volume 29, Issue 5, Aug. 2019.  公式リンク  
  
• Yoshitaka Ishii. Structural Analysis of the Terminal Groups in Commercial Hevea Natural Rubber by 2D-NMR with DOSY Filters and Multiple-WET Methods Using Ultrahigh-Field NMR, Biomacromolecules, vol. 20, 3, pp. 1394-1400, Feb. 2019.  公式リンク  
  
• B. Yoo, Y. Xiao, D. McElheny, Y. Ishii. E22G pathogenic mutation of β-amyloid (Aβ) enhances misfolding of Aβ40 by unexpected prion-like cross talk between Aβ42 and Aβ40, J. Am. Chem. Soc, Vol. 140, No. 8, pp. 2781–2784, Feb. 2018.
• Yoshitaka Ishii, Ayesha Wickramasinghe, Isamu Matsuda, Yuki Endo, Yuji Ishii, Yusuke Nishiyama, Takahiro Nemoto, Takayuki Kamihara. Progress in proton-detected solid-state NMR (SSNMR): Super-fast 2D SSNMR collection for nano-mole-scale proteins, Journal of Magnetic Resonance, Vol. 286, pp. 99-109, Jan. 2018.  公式リンク  
  
• Thomas J. Nacken, Christian E. Halbig, Simon E. Wawra, Cornelia Damm, Stefan Romeis, Johannes Walter, Mohammad J. Tehrani, Yichen Hu, Yoshitaka Ishii, Siegfried Eigler, Wolfgang Peukert. Structural factors controlling size reduction of graphene oxide in liquid processing, Carbon, Vol. 125, pp. 360-369, Sept. 2017.
• Yichen Hu, Yeonjun Shim, Junghoon Oh, Sunghee Park, Sungjin Park, Yoshitaka Ishii. Synthesis of 13C‑,15N‑labeled graphitic carbon nitrides and NMR-based evidence of hydrogen-bonding assisted two-dimensional assembly, Chemistry of Materials, Vol. 29, pp. 5080-5089, May 2017.

国際会議発表 (査読有り)

• Y. Ishii. Sensitivity-Enhanced Protein Solid-state NMR using Ultra-fast MAS and Structural Studies of Alzheimer’s Amyloid-β, 2nd India-Japan Workshop on Magnetic Resonance, Dec. 2019.

国際会議発表 (査読なし・不明)

• Konishi Fumito, Matsuda Isamu, Matsunaga Tatsuya, Ishii Yoshitaka. Structural stabilization for further analysis of Aβ42 oligomers by solid-state NMR, The 62th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2023.
• Konishi Fumito, Matsuda Isamu, Matsunag Tatsuya, Takahashi Masato, Yamazaki Toshio, Yanagisawa Yoshinori, Piao Renzhong, Endo Yuuki, Hachitani Kenichi, Kato Hiroshi, Nemoto Takahiro, Ishii Yoshitaka. Solid-state NMR experiment on over 1 GHz magnet and Magic-angle spinning on over 160 kHz with a new probe, The 62th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2023.
• Yoshitaka Ishii. Innovations in sensitivity-enhanced protein solid-state NMR and applications to amyloid proteins: past, present, and future, Asia Pacific NMR 2023, Sept. 2023.
• Matsunaga Tatsuya, Okabe Ryotaro, Matsuda Isamu, Yamazaki Toshio, Ishii Yoshitaka. Development of CP and Solvent Suppression Methods for 1H-Detected Solid-State NMR Using Ultra-Fast MAS, Asia Pacific NMR 2023, Sept. 2023.
• Matsunaga Tatsuya, Takahashi Ryo, So Tsukito, Ishii Yoshitaka. Efficient 13C–13CO Selective Polarization Transfer Under Ultra-fast MAS For Multi-dimensional Protein Solid-state-NMR, Asia Pacific NMR 2023, Sept. 2023.
• Kodama Yu, Matsuda Isamu, Mohammad Tehrani, Kobayashi Nobuhiro, Ishii Yoshitaka. Structural Stability of Cross-seeded Fibers of Aβ40, Aβ42,and E22G Aβ40 by Molecular Dynamics and Solid-state NMR, Asia Pacific NMR 2023, Sept. 2023.
• Wickramasinghe Ayesha, Xiao Yiling, Yagi-Utsumi Maho, Kato Koichi, Ishii Yoshitaka. Expeditious Characterization of Aβ Fibrils by 1H-detected SSNMR, ISMAR 2023, Aug. 2023.
• Yoshitaka Ishii. Sensitivity enhanced protein solid-state NMR using ultra-fast MAS and its applications to amyloid proteins: innovations and dilemma, ISMAR 2023, Aug. 2023.
• Yanagisawa Y., Suetomi Y., Piao R., Yamazaki T., Ono M., Yoshikawa M., Hamada M., Saito K., Maeda H., Matsunaga T., Hamatsu J., Endo Y., Nemoto T., Hachitani K., Ishii Y.. New advances toward development of a 1.3 GHz NMR system: 1.01 GHz NMR system and MAS beyond 150 kHz, Euromar 2023, July 2023.
• Yanagisawa Yoshinori, Suetomi Yu, Piao Renzhong, Yamazaki Toshio, Ono Michitaka, Yoshikawa Masatoshi, Hamada Mamoru, Saito Kazuyoshi, Maeda Hidaki, Matsunaga Tatsuya, Hamatsu Jyunpei, Nishiyama Yusuke, Hachitani Kenichi, Ishii Yoshitaka. Development and applications of a 1.01 GHz (23.7 T) NMR system, ENC 2023, Apr. 2023.
• Yoshitaka Ishii. Structure and misfolding kinetics of amyloid-β fibrils & oligomers studied by solid-state NMR (SSNMR) and cryoEM, Amyloid symposium, Feb. 2023.
• Yoshitaka Ishii. Structure and misfolding kinetics of amyloid-β fibrils & oligomers studied by solid-state NMR (SSNMR) and cryoEM, 3rd Japan-India NMR symposium, Feb. 2023.
• Yoshitaka Ishii. Innovations in protein solid-state NMR using ultra-fast MAS and its applications to amyloid-beta fbrils, Euromar 2022, July 2022.
• Yoshitaka Ishii. Innovation in Protein SSNMR using Ultra-fast MAS and New Polymorphs of Alzheimer’s Amyloid-beta, ICMRBS Web Seminar, Oct. 2020.
• Y. Ishii. Solid-state NMR Studies of Amyloid Fibrils and Oligomers, 5th Polish-Korean Conference on Protein Folding - Theoretical and Experimental Approaches, Sept. 2019.
• Y. Ishii. Innovations by High-Speed MAS SSNMR and SSNMR Studies of Misfolded Amyloid-β, Telluride Conference “Emerging Methodologies for Paramagnetic NMR and Dynamic Nuclear Polarization in Biological and Inorganic Materials”, Aug. 2019.
• Yoshitaka Ishii, Takayuki Kamihara, Isamu Matsuda, Yiling Xiao. Sensitivity-enhanced protein solid-state NMR using ultra-fast MAS and structural studies of Alzheimer’s amyloid-β, EUROISMAR 2019, Aug. 2019.
• Takaya Ishiguro, Isamu Matsuda, Yoshitaka Ishii. Solid-state NMR Studies of Cross-seeding of Aβ40 with Aβ42 fibril, EUROISMAR 2019, Aug. 2019.
• Ryo Takahashi, Yuki Miyazaki, Tatsuya Matsunaga, Takayuki Kamihara, Yoshitaka Ishii. New progress toward high-dimensional biomolecular SSNMR, EUROISMAR 2019, Aug. 2019.
• Yuki Miyazaki, Ryo Takahashi, Isamu Matsuda, Toshio Yamazaki, Yoshitaka Ishii. New Method for Selective Deuteration of Side-Chains for High-Resolution Protein SSNMR, EUROISMAR 2019, Aug. 2019.
• Y. Ishii. “Innovations” by High-speed-MAS SSNMR, ISMAR Conversation on “High-Speed Magic-Angle Spinning: What are the Advantages and Limitations?”, June 2019.
• Y. Ishii. Protein Solid-state NMR using Ultra-fast MAS and Structural Studies of Alzheimer’s Amyloid-beta, 3rd Chinese Biomolecular NMR Meeting, May 2019.
• Yamazaki T., Yanagisawa Y., Piao R., Suetomi Y., Yamagishi K., Takahashi M., Takao T., Ohki K., Yamaguchi T., Nagaishi T., Miyoshi Y., Yoshikawa M., Hamada M., Saito K., Kitaguchi H., Hachitani K., Ishii Y., Maeda, H.. Towards 1.3 GHz NMR: A Persistent 400 MHz NMR with Superconducting Joints for High-Temperature Superconductors, Experimental NMR Conference, Apr. 2019.
• Y. Ishii. Prion-like propagation and structural conversion of Alzheimer's amyloid-beta: solid-state NMR studies, The 6th International Symposium on Drug Discovery and Design by NMR, Nov. 2018.
• Y. Ishii. Solid-state NMR Studies Reveal Prion-like Propagation and Structural Conversion of Alzheimer's Amyloid-beta, Asia Pacific Prion Symposium 2018, Oct. 2018.
• Y. Ishii. Prion-like propagation and structural conversion of Alzheimer's amyloid-beta: solid-state NMR studies, ICMRBS 2018, Aug. 2018.
• Y. Ishii. Solid-state NMR Studies of Graphene-based Systems and Nano-mole-scale Protein Solid-state NMR using Ultra-fast MAS, Experimental NMR conference, May 2018.
• Y. Ishii. Social Impact of the 1.3 GHz NMR Project, JST-Mirai Kick-off Symposium, Mar. 2018.
• Y. Ishii. Solid-state NMR (SSNMR) studies of graphene-based systems and nano-mole-scale protein SSNMR using ultra-fast MAS, ACS National Meeting, ACS national meeting, Mar. 2018.

国内会議発表 (査読なし・不明)

• So Tsukito, Matsunaga Tatsuya, Takahashi Ryo, Ishii Yoshitaka. Efficient 13Cα–13CO selective magnetization transfer under ultra-fast MAS for multi-dimensional protein solid-state-NMR, The 62th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2023.
• 松永 達弥, 石井 佳誉. πパルストレインを用いた高速MAS下での13C–13C DARR測定手法の開発, The 61th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2023.
• 寺見 響, 重光 佳基, 石井 佳誉. 固体NMRを用いたヒト脳由来Aβ42線維の研究における試料の最適化と構造解析, The 61th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2022.
• Ayesha Wickramasinghe, Yoshitaka Ishii. High-dimensional 1H-detected SSNMR for Expeditious Characterization of Aβ42 Fibrils, The 61th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2022.
• Ayesha Wickramasinghe, Tatsuya Matsunaga, Isamu Matsuda, Mohammad Jafar Tehrani, Hibik Terami, Yoshiki Shigemitsu, Naohiro Kobayashi, Yoshitaka Ishii. Innovations in High-field Protein Solid-state NMR and its Applications to Amyloid-beta Fibrils and Other Biomolecules, The 61th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2022.
• Li Bing Kee, Takayuki Kamihara, Tatsuya Matsunaga, Yoshiki Shigemitsu, Isamu Matsuda, Yoshitaka Ishii. Aggregation kinetics and structural insight of α-synuclein monomers cross-seeded with β-amyloid fibrils, The 61st Annual Meeting of the Nuclear Magnetic Resonance Society of Japan (2022), Nov. 2022.  公式リンク  
  
• Yoshitaka Ishii. Revealing Novel Polymorphs and Cross Propagation for 42-residue Amyloid beta by Solid-state NMR, 日本生物物理学会, Sept. 2022.
• 石井 佳誉. Development of Solid-state NMR (SSNMR) Methods using Ultra-fast MAS and Applications of High-field SSNMR to Amyloid Proteins and Other Systems, 固体NMR材料フォーラム, May 2022.
• Aeysha Wickramasinghe, Yiling Xiao, Nobuyuki Kobayashi, Toshio Yamazaki, Yoshitaka Ishii. Structural Differences and Novel Polymorphs of Synthetic and Brain-derived Aβ42 Fibrils by 1H-detected SSNMR, The 59th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2020.
• 柏原功典, 大内宗城, 北浦健大, 石井佳誉. NMR測定と量子化学計算による加硫天然ゴムの構造解析, 第59回NMR討論会 (2020), Nov. 2020.
• 松永 達弥, 岡部 遼太郎, 石井 佳誉. Adiabatic Pulseを用いた溶媒信号抑制パルスの開発および固体NMR測定への応用, 第59回NMR討論会 (2020), Nov. 2020.
• 松永 達弥, 高橋 涼, 石井 佳誉. Band-selective CP法を使った超高速MASにおける 高効率13C-13C、13C-1H間磁化移動の実現, 第59回NMR討論会 (2020), Nov. 2020.
• 中田拳太, 松永達也, 石井佳誉. New cross polarization method for solid-state NMR measurement, 第59回NMR討論会 (2020), Nov. 2020.
• 大山 貴子, 高橋葉月, 山崎俊夫, Piero Carninci, 石井佳誉. 機能性長鎖ノンコーディングRNA SINEUP機能ドメインの2次構造決定, 第59回NMR討論会 (2020), Nov. 2020.
• Mohammad Jafar Tehrani, Yoshitaka Ishii. Towards structural determination of E22G mutated Aβ40 fibrils by solid-state NMR spectroscopy, The 59th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2020.
• Zixuan Wei, Yoshiki Shigemitsu, Tatsuya Matsunaga, Isamu Matsuda, Yoshitaka Ishii. Alpha-synuclein Aggregation Kinetics and Structural Insight in the Presence of β-amyloid Fibrils, The 59th Annual Meeting of the Nuclear Magnetic Resonance Society of Japan, Nov. 2020.
• 石井 佳誉. Recent Progress in High-field Biomolecular Solid-state NMR and Beyond, Yokohama NMR, Oct. 2020.
• 高橋涼, 松永達弥, 神原孝之, 石井佳誉. New progress toward high-dimensional biomolecular SSNMR, 第58回NMR討論会(2019), Nov. 2019.
• 宮崎勇輝, 高橋涼, 松田勇, 山崎俊夫, 石井佳誉. タンパク質の固体NMR分解能向上のための側鎖選択的重水素標識法の開発, 第58回NMR討論会(2019), Nov. 2019.
• 藤田健太郎, 松田勇, 石黒貴也, 石井佳誉. 固体NMRを用いたAβ(1-42)線維へのEGCG添加による構造変化の検出, 第58回NMR討論会(2019), Nov. 2019.
• 柏原功典, 石井佳誉, Ruoff Rodney. 固体NMR測定と量子科学計算によるポーラスカーボンの構造モデリング, 第58回NMR討論会(2019), Nov. 2019.
• Ayesha Wickramasinghe, Yiling Xiao, Naohiro Kobayashi, Yoshitaka Ishii. Structural characterization of Abeta(1-42) fibril in nano-mole scale by 1H-detected SSNMR under UFMAS, The 58th Annual Meeting of the NMR Society of Japan (2019), Nov. 2019.
• 松永 達弥, 岡部 遼太郎, 石井 佳誉. 固体NMR測定におけるAdiabatic Pulseを用いた溶媒信号抑制パルスの開発, 第58回NMR討論会(2019), Nov. 2019.
• Y. Ishii, Y. Xiao, B. Yoo, I. Matsuda, D. McElheny. Unexpected Prion-like Cross Talk between Abeta42 and Abeta40 studied by solid-state NMR, 第５８回 NMR討論会, Nov. 2019.
• Y. Ishii. Recent progress of high-resolution solid-state NMR: Applications to misfolded amyloid-beta proteins and graphene-based systems, 理研シンポジウム 「第19 回分析・解析技術と化学の最先端」, Dec. 2018.
• Y. Ishii. Biomolecular solid-state NMR: recent advances & applications to amyloid protein, 日本分光学会NMR分光部会, Oct. 2018.
• 高橋涼, Ayesha Wickramasinghe, 松田勇, 松永達弥, 神原孝之, 山崎俊夫, 石井佳誉. 高次元固体NMR測定の高速化, 第57回NMR討論会, Sept. 2018.  公式リンク  
  
• Y. Ishii, Y. Xiao, B. Yoo, I. Matsuda, D. McElheny. E22G pathogenic mutation of beta-amyloid (Ab) enhances misfolding of Ab40 by unexpected prion-like cross talk between Ab42 and Ab40, The 57-th Annual Meeting of the Nuclear Magnetic Resnance Society of Japan, Sept. 2018.
• Y. Ishii. Protein structures define misfolding and prion-like propagation of Alzheimer's amyloid-beta: solid-state NMR studies, The 56-th Annual Meeting of Biophysical Society of Japan, Sept. 2018.

その他の論文・著書など

• Yiling Xiao, Dan McElheny, Minako Hoshi, Yoshitaka Ishii. Solid state NMR studies of amyloid materials: a protocol to define an atomic model of Aβ(1–42) in amyloid fibrils, Methods in Molecular Biology, May 2018.

特許など

• 石井佳誉, 大内　宗城, 北浦　健大. 環状スルフィド構造の定量方法. 特許. 公開. 国立大学法人東京工業大学, 住友ゴム工業株式会社, 独立行政法人理化学研究所. 2020/11/11. 特願2020-188025. 2022/05/23. 特開2022-077256. 2022.

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