論文

• Shiela Marie Selisana, Xinyue CHEN, Mahfudhoh E, Anom Bowolaksono, Anna Rozaliyani, Kanami Orihara, Susumu Kajiwara. Alteration of β-glucan in the emerging fungal pathogen Candida auris leads to immune evasion and increased virulence., Medical microbiology and immunology, July 2024.  公式リンク  
  
• Du Y, Kusama K, Hama K, Chen X, Tahara Y, Kajiwara S, Shibata S, Orihara K.. Protective Effects of Inulin on Stress-Recurrent Inflammatory Bowel Disease., International Journal of Molecular Sciences, Feb. 2024.
• Lin M, Huang Y, Orihara K, Chibana H, Kajiwara S, Chen X. A Putative NADPH Oxidase Gene in Unicellular Pathogenic Candida glabrata Is Required for Fungal ROS Production and Oxidative Stress Response., Journal of Fungi, Dec. 2023.
• Mengying Lyu, Yuying Bai, Kanami Orihara, Kazuhiko Miyanaga, Naoyuki Yamamoto. GAPDH Released from Lactobacillus johnsonii MG Enhances Barrier Function by Upregulating Genes Associated with Tight Junctions, Microorganisms, May 2023.  公式リンク  
  
• Kazuto SHIGA, Atsushi HARAGUCHI, Hiroyuki SASAKI, Yu TAHARA, Kanami ORIHARA, Shigenobu SHIBATA. Effect of circadian clock and claudin regulations on inulin-induced calcium absorption in the mouse intestinal tract, Bioscience of Microbiota, Food and Health, Vol. 42, No. 2, pp. 114-123, 2023.  公式リンク  
  
• Yean Sheng Lee, Xinyue Chen, Tria Widiasih Widiyanto, Kanami Orihara, Hiroyuki Shibata, Susumu Kajiwara. Curcumin affects function of Hsp90 and drug efflux pump of Candida albicans, Front Cell Infect Microbiol, Sept. 2022.
• Kanami Orihara. Regulating peripheral clocks to restore skin immunity., アレルギーの臨床, Aug. 2022.
• K. Orihara, S. O. Odemuyiwa, W. P. Stefura, R. Ilarraza, K. T. HayGlass, R. Moqbel. Neurotransmitter signalling via NMDA receptors leads to decreased T helper type 1-like and enhanced T helper type 2-like immune balance in humans, Immunology, Vol. 153, No. 3, pp. 368-379, Mar. 2018.  公式リンク  
  
• H. Morita, H. Suzuki, K. Orihara, K. Motomura, A. Matsuda, Y. Ohya, H. Saito, I. Nomura, K. Matsumoto. Food protein-induced enterocolitis syndromes with and without bloody stool have distinct clinicopathologic features, J Allergy Clin Immunol, Dec. 2017.  公式リンク  
  
• M. Sato, T. Shoda, H. Shimizu, K. Orihara, K. Futamura, A. Matsuda, Y. Yamada, R. Irie, T. Yoshioka, T. Shimizu, Y. Ohya, I. Nomura, K. Matsumoto, K. Arai. Gene Expression Patterns in Distinct Endoscopic Findings for Eosinophilic Gastritis in Children, J Allergy Clin Immunol Pract, Nov. 2017.  公式リンク  
  
• T. Shoda, A. Matsuda, I. Nomura, N. Okada, K. Orihara, H. Mikami, N. Ishimura, S. Ishihara, K. Matsumoto, Y. Kinoshita. Eosinophilic esophagitis versus proton pump inhibitor-responsive esophageal eosinophilia: Transcriptome analysis, J Allergy Clin Immunol, Vol. 139, No. 6, pp. 2010-2013 e4, June 2017.  公式リンク  
  
• M. Wada, K. Orihara, M. Kamagata, K. Hama, H. Sasaki, A. Haraguchi, H. Miyakawa, A. Nakao, Shigenobu Shibata. Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice, Sci Rep, Vol. 7, No. 1, pp. 8802, 2017.  公式リンク  
  
• T. Shoda, A. Matsuda, K. Arai, H. Shimizu, H. Morita, K. Orihara, N. Okada, M. Narita, Y. Ohya, H. Saito, K. Matsumoto, I. Nomura. Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 levels, J Allergy Clin Immunol, Vol. 138, No. 1, pp. 299-303, July 2016.  公式リンク  
  
• V. Anaparti, R. Ilarraza, K. Orihara, G. L. Stelmack, O. O. Ojo, T. H. Mahood, H. Unruh, A. J. Halayko, R. Moqbel. NMDA receptors mediate contractile responses in human airway smooth muscle cells, Am J Physiol Lung Cell Mol Physiol, Vol. 308, No. 12, pp. L1253-64, June 2015.  公式リンク  
  
• K. Tanabe, E. Kitagawa, M. Wada, A. Haraguchi, K. Orihara, Y. Tahara, A. Nakao, Shigenobu Shibata. Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model, Sci Rep, Vol. 5, pp. 14424, 2015.  公式リンク  
  
• Z. Mou, D. Liu, I. Okwor, P. Jia, K. Orihara, J. E. Uzonna. MHC class II restricted innate-like double negative T cells contribute to optimal primary and secondary immunity to Leishmania major, PLoS Pathog, Vol. 10, No. 9, pp. e1004396, Sept. 2014.  公式リンク  
  
• H. Morita, I. Nomura, K. Orihara, K. Yoshida, A. Akasawa, H. Tachimoto, Y. Ohtsuka, Y. Namai, M. Futamura, T. Shoda, A. Matsuda, N. Kamemura, H. Kido, T. Takahashi, Y. Ohya, H. Saito, K. Matsumoto. Antigen-specific T-cell responses in patients with non-IgE-mediated gastrointestinal food allergy are predominantly skewed to T(H)2, J Allergy Clin Immunol, Vol. 131, No. 2, pp. 590-2 e1-6, Feb. 2013.  公式リンク  
  
• K. Futamura*, K. Orihara*, N. Hashimoto, H. Morita, S. Fukuda, H. Sagara, K. Matsumoto, Y. Tomita, H. Saito, A. Matsuda. beta2-Adrenoceptor agonists enhance cytokine-induced release of thymic stromal lymphopoietin by lung tissue cells, Int Arch Allergy Immunol, Vol. 152, No. 4, pp. 353-61, Feb. 2010.  公式リンク  
  
• A. Yagami*, K. Orihara*, H. Morita, K. Futamura, N. Hashimoto, K. Matsumoto, H. Saito, A. Matsuda. IL-33 mediates inflammatory responses in human lung tissue cells, J Immunol, Vol. 185, No. 10, pp. 5743-50, 2010.  公式リンク  
  
• Y. Enomoto, K. Orihara, T. Takamasu, A. Matsuda, Y. Gon, H. Saito, C. Ra, Y. Okayama. Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack, J Allergy Clin Immunol, Vol. 124, No. 5, pp. 913-20 e1-7, Nov. 2009.  公式リンク  
  
• K. Orihara, H. Morita, A. Yagami, N. Kajiwara, S. Nakae, K. Matsumoto, H. Nagasaki, Y. Saito, H. Saito, A. Matsuda. TH2 cytokines potently induce an appetite-stimulating peptide, melanin-concentrating hormone, in human vascular endothelial cells, J Allergy Clin Immunol, Vol. 124, No. 3, pp. 612-4, 614 e1-2, Sept. 2009.  公式リンク  
  
• A. Matsuda, K. Orihara, S. Fukuda, H. Fujinaga, K. Matsumoto, H. Saito. Corticosteroid enhances TNF-alpha-mediated leukocyte adhesion to pulmonary microvascular endothelial cells, Allergy, Vol. 63, No. 12, pp. 1610-6, Dec. 2008.  公式リンク  
  
• K. Orihara, M. Narita, T. Tobe, A. Akasawa, Y. Ohya, K. Matsumoto, H. Saito. Circulating Foxp3+CD4+ cell numbers in atopic patients and healthy control subjects, J Allergy Clin Immunol, Vol. 120, No. 4, pp. 960-2, Oct. 2007.  公式リンク  
  
• T. Negoro, K. Orihara, T. Irahara, H. Nishiyama, K. Hagiwara, R. Nishida, H. Takagi, K. Satoh, Y. Yamamoto, S. Shimizu, T. Hagiwara, M. Ishii, T. Tanioka, Y. Nakano, K. Takeda, I. Yoshimura, Y. Iikura, T. Tobe. Influence of SNPs in cytokine-related genes on the severity of food allergy and atopic eczema in children, Pediatr Allergy Immunol, Vol. 17, No. 8, pp. 583-90, Dec. 2006.  公式リンク  
  
• K. Orihara, TAKASHI YAMAZAKI, R. Shinkyo, T. Sakaki, K. Inouye, A. Tsukamoto, J. Sugiura, KAZUO SHISHIDO. Rat cytochrome P450-mediated transformation of dichlorodibenzo-p-dioxins by recombinant white-rot basidiomycete Coriolus hirsutus, Appl Microbiol Biotechnol, Vol. 69, No. 1, pp. 22-8, Nov. 2005.  公式リンク  
  

国際会議発表 (査読有り)

• Orihara K, Du Y, Kusama K, Chen X, Kajiwara S.. Protective Effects of Inulin on Stress-Recurrent Inflammatory Bowel Disease, Japanese Society for Immunology, Jan. 2024.
• Vibriani A, Kajiwara S, Orihara K.. Opsin molecule: A potential communicator between the circadian rhythm and skin-epithelial barrier (immunity) upon blue light exposure, Japanese Society for Immunology, Jan. 2024.
• Low J, Orihara K, Kajiwara S. Circadian Dysregulation in HaCaT keratinocytes Upon Candida albicans Infection, Japanese Society for Immunology, Jan. 2024.

国内会議発表 (査読有り)

• 福永もえ, Chen Xinyue, 梶原将, 山本直之, 折原芳波. 乳由来オピオイドペプチドβ-Casomorphin-10の概日リズムへの影響評価, 日本食品免疫学会学術大会, Nov. 2023.
• Du Y, Chen X, Kajiwara K, Orihara K.. Urolithins regulating circadian ryhthms in immunity on intestinal epithelial cells, 日本時間生物学会, Sept. 2023.

国際会議発表 (査読なし・不明)

• Xinyue Chen, Huang Yao, Hiroji Chibana, Kanami Orihara, Susumu Kajiwara. Roles of a putative NADPH oxidase gene in Candida glabrata., 19th Asia Pacific Congress of Clinical Microbiology and Infection (APCCMI 2023), July 2023.

国内会議発表 (査読なし・不明)

• Jing Jing, Tenagy, Kengo Tejima, Xinyue Chen, Kanami Orihara, Susumu Kajiwara. Effect of triacsin C to Malassezia acyl-CoA synthetases, 2023年度日本生化学会関東支部例会, June 2023.
• Kanami Orihara. Regulating peripheral clocks to restore epithelial immunity, International Drug Discovery Science & Technology, May 2023.
• Shiela Selisana, Xinyue Chen, Kanami Orihara, Susumu Kajiwara.. Hypoxia, lactate, and low and high pH trigger cell wall remodelling in Candida auris, 第95回日本生化学会大会, Nov. 2022.
• Lin Maoyi, Maho Shirai, Xinyue Chen, Kanami Orihara, Susumu Kajiwara. Analysis of hepatocyte apoptosis induction mechanism by Candida species, 第95回日本生化学会大会, Nov. 2022.

その他の論文・著書など

• Kanami Orihara. Skin and immune cells crosstalk via circadian regulations, Exploration of Immunology, Open Exploration, Vol. 1, p. 285-294, Oct. 2021.  公式リンク  
  
• 折原芳波. 末梢時計を制御してアレルギー病態の悪化を防ぐ, アレルギーの臨床, 北隆館, Vol. 41, No. 11, p. 76−79, Aug. 2021.
• 折原芳波. 体内時計を活用したアレルギー炎症制御, Medical Science Digest, ニューサイエンス社, Vol. 47, No. 8, p. 38-40, July 2021.
• Kanami Orihara, Atsushi Haraguchi, Shigenobu Shibata. Crosstalk Among Circadian Rhythm, Obesity and Allergy, International Journal of Molecular Sciences, Vol. 21, No. 5, pp. 1884, Mar. 2020.  公式リンク  
  
• T. Shoda, K. Futamura, K. Orihara, M. Emi-Sugie, H. Saito, K. Matsumoto, A. Matsuda. Recent advances in understanding the roles of vascular endothelial cells in allergic inflammation, Allergol Int, Vol. 65, No. 1, pp. 21-9, Jan. 2016.  公式リンク  
  
• K. Orihara, H. Saito. Controlling the peripheral clock might be a new treatment strategy in allergy and immunology, J Allergy Clin Immunol, Vol. 137, No. 4, pp. 1236-7, 2016.  公式リンク  
  
• K. Orihara, N. Dil, V. Anaparti, R. Moqbel. What's new in asthma pathophysiology and immunopathology?, Expert Rev Respir Med, Vol. 4, No. 5, pp. 605-29, Oct. 2010.  公式リンク  
  
• K. Orihara, A. Matsuda. Pathophysiological roles of microvascular alterations in pulmonary inflammatory diseases: possible implications of tumor necrosis factor-alpha and CXC chemokines, Int J Chron Obstruct Pulmon Dis, Vol. 3, No. 4, pp. 619-27, Dec. 2008.  公式リンク  
  
• K. Orihara, S. Nakae, R. Pawankar, H. Saito. Role of regulatory and proinflammatory T-cell populations in allergic diseases, World Allergy Organ J, Vol. 1, No. 1, pp. 9-14, Jan. 2008.  公式リンク  
  

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