論文

• John Clyde CoSoriano, Shiho Tsutsumi, Daiya Ohara, Keiji Hirota, Gen Kondoh, Tatsuya Niwa, Hideki Taguchi, Tetsuya Kadonosono*, Shinae Kizaka-Kondoh. Identification of surface markers and functional characterization of myeloid derived suppressor cell-like adherent cells, Adv Biol (Weinh), Vol. 8, No. 3, pp. e2300159, Mar. 2024.
• Matsumoto R, Niwa T, Shimane Y, Kuruma Y, Hideki Taguchi, Takashi Kanamori. Regulated N-Terminal Modification of Proteins Synthesized Using a Reconstituted Cell-Free Protein Synthesis System., ACS synthetic biology, June 2023.  公式リンク  
  
• Inoue R, Yosuke Fukutani, Niwa T, Matsunami H, Masafumi Yohda. Identification and Characterization of Proteins That Are Involved in RTP1S-Dependent Transport of Olfactory Receptors., International journal of molecular sciences, Apr. 2023.  公式リンク  
  
• Minami S, Niwa T, Uemura E, Koike R, Taguchi H, Motonori Ota. Prediction of chaperonin GroE substrates using small structural patterns of proteins., FEBS open bio, Mar. 2023.  公式リンク  
  
• Yamakawa A, Niwa T, Chadani Y, Kobo A, Hideki Taguchi. A method to enrich polypeptidyl-tRNAs to capture snapshots of translation in the cell., Nucleic acids research, Jan. 2023.  公式リンク  
  
• Haruka Onodera, Tatsuya Niwa, Hideki Taguchi, Yuhei Chadani. Prophage excision switches the primary ribosome rescue pathway and rescue‐associated gene regulations in Escherichia coli, Molecular Microbiology, Jan. 2023.  公式リンク  
  
• Yosuke Ito, Yuhei Chadani, Tatsuya Niwa, Ayako Yamakawa, Kodai Machida, Hiroaki Imataka, Hideki Taguchi. Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes, Nature Communications, Dec. 2022.  公式リンク  
  
• Tatsuya Niwa, Nakazawa K, Hoshi K, Tadakuma H, Ito K, Taguchi H. Application of fluorescence correlation spectroscopy to investigate the dynamics of a ribosome-associated trigger factor in Escherichia coli., Frontiers in molecular biosciences, Aug. 2022.  公式リンク  
  
• Tatsuya Niwa, Yuhei Chadani, Hideki Taguchi. Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli, Molecules, June 2022.  公式リンク  
  
• Hirai K, Yamashita H, Shusuke TOMOSHIGE, Mishima Y, Tatsuya Niwa, Kenji Ohgane, Ishii M, Kanamitsu K, Ikemi Y, Nakagawa S, Hideki Taguchi, Shinichi Sato, Hashimoto Y, Minoru Ishikawa. Conversion of a PROTAC Mutant Huntingtin Degrader into Small-Molecule Hydrophobic Tags Focusing on Drug-like Properties., ACS medicinal chemistry letters, Feb. 2022.  公式リンク  
  
• Tsushima M, Shinichi Sato, Kazuki Miura, Tatsuya Niwa, Taguchi H, Hiroyuki Nakamura. Intracellular photocatalytic-proximity labeling for profiling protein-protein interactions in microenvironments., Chemical communications (Cambridge, England), Feb. 2022.  公式リンク  
  
• Nakagawa Y, Shen HC, Komi Y, Shinju Sugiyama, Kurinomaru T, Tomabechi Y, Krayukhina E, Kenji Okamoto, Yokoyama T, Mikako Shirouzu, Uchiyama S, Inaba M, Tatsuya Niwa, Yasushi Sako, Hideki Taguchi, Motomasa Tanaka. Amyloid conformation-dependent disaggregation in a reconstituted yeast prion system., Nature chemical biology, Feb. 2022.  公式リンク  
  
• Yuhei Chadani, Sugata N, Tatsuya Niwa, Ito Y, Shintaro Iwasaki, Hideki Taguchi. Nascent polypeptide within the exit tunnel stabilizes the ribosome to counteract risky translation., The EMBO journal, Oct. 2021.  公式リンク  
  
• Hitoki Nanaura, Kawamukai H, Fujiwara A, Uehara T, Yuichiro Aiba, Nakanishi M, Shiota T, Hibino M, Pattama Wiriyasermkul, Kikuchi S, Riko Nagata, Masaya Matsubayashi, Yoichi Shinkai, Tatsuya Niwa, Taro Mannen, Naritaka Morikawa, Iguchi N, Takao Kiriyama, Ken Morishima, Inoue R, Masaaki Sugiyama, Oda T, Kodera N, Toma-Fukai S, Sato M, Hideki Taguchi, Shushi Nagamori, Osami Shoji, Koichiro Ishimori, Hiroyoshi Matsumura, Sugie K, Tomohide Saio, Yoshizawa T, Eiichiro Mori. C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers., Nature communications, Sept. 2021.  公式リンク  
  
• Deschoenmaeker F, Mihara S, Tatsuya Niwa, Taguchi H, Ken-ichi Wakabayashi, Toyoshima M, Shimizu H, Hisabori T. Thioredoxin pathway in Anabaena sp. PCC 7120: activity of NADPH-thioredoxin reductase C., Journal of biochemistry, Sept. 2021.  公式リンク  
  
• Tomohiro Shimada, Kohta Nakazawa, Tomoyuki Tachikawa, Natsumi Saito, Tatsuya Niwa, Hideki Taguchi, Kan Tanaka. Acetate overflow metabolism regulates a major metabolic shift after glucose depletion in Escherichia   coli, FEBS Letters, Aug. 2021.  公式リンク  
  
• Tony Z. Jia, Po-Hsiang Wang, Tatsuya Niwa, Irena Mamajanov. Connecting Primitive Phase Separation to Biotechnology, Journal of Biosciences, Vol. 46, Aug. 2021.
• Keita Nakane, Shinichi Sato, Tatsuya Niwa, Tsushima M, Shusuke TOMOSHIGE, Hideki Taguchi, Minoru Ishikawa, Hiroyuki Nakamura. Proximity Histidine Labeling by Umpolung Strategy Using Singlet Oxygen., Journal of the American Chemical Society, Apr. 2021.  公式リンク  
  
• Aleksandar Zdravković, James M. Daley, Arijit Dutta, Tatsuya Niwa, Yasuto Murayama, Shuji Kanamaru, Kentaro Ito, Takahisa Maki, Bilge Argunhan, Masayuki Takahashi, Hideo Tsubouchi, Patrick Sung, Hiroshi Iwasaki. A conserved Ctp1/CtIP C-terminal peptide stimulates Mre11 endonuclease activity, Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, Vol. 118, No. 11, e2016287118, Mar. 2021.  公式リンク  
  
• Shinya Sugimoto, Kunitoshi Yamanaka, Tatsuya Niwa, Yurika Terasawa, Yuki Kinjo, Yoshimitsu Mizunoe, Teru Ogura. Hierarchical Model for the Role of J-Domain Proteins in Distinct Cellular Functions, Journal of Molecular Biology, Elsevier, Volume 433, Issue 3, Feb. 2021.  公式リンク  
  
• Mai Duy Luu Trinh, Daichi Miyazaki, Sumire Ono, Jiro Nomata, Masaru Kono, Hiroyuki Mino, Tatsuya Niwa, Yuki Okegawa, Ken Motohashi, Hideki Taguchi, Toru Hisabori, Shinji Masuda. The evolutionary conserved iron-sulfur protein TCR controls P700 oxidation in photosystem I, iScience, Feb. 2021.  公式リンク  
  
• Masuzawa T, Shinichi Sato, Tatsuya Niwa, Taguchi H, Hiroyuki Nakamura, Takanori Oyoshi. G-quadruplex-proximity protein labeling based on peroxidase activity., Chemical communications (Cambridge, England), Sept. 2020.  公式リンク  
  
• Daiki Kashiwagi, Hao K Shen, Seunghyun Sim, Koki Sano, Yasuhiro Ishida, Ayumi Kimura, Tatsuya Niwa, Hideki Taguchi, Takuzo Aida. Molecularly Engineered "Janus GroEL": Application to Supramolecular Copolymerization with a Higher Level of Sequence Control., Journal of the American Chemical Society, July 2020.  公式リンク  
  
• Tony Z Jia, Kosuke Fujishima, Tatsuya Niwa. 液ー液相分離と生命の起源, 生物工学会誌, 98, 5, 236-240, May 2020.  公式リンク  
  
• Mikihisa Muta, Ryo Iizuka, Tatsuya Niwa, Yuanfang Guo, Hideki Taguchi, Takashi Funatsu. Nascent SecM chain interacts with outer ribosomal surface to stabilize translation arrest., The Biochemical journal, Vol. 477, No. 2, pp. 557-566, Jan. 2020.  公式リンク  
  
• Michihiko Tsushima, Shinichi Sato, Tatsuya Niwa, HIDEKI TAGUCHI, Hiroyuki Nakamura. Catalyst-proximity protein chemical labelling on affinity beads targeting endogenous lectins., Chemical communications (Cambridge, England), Vol. 55, No. 88, Page 13275-13278, Oct. 2019.  公式リンク  
  
• Tatsuya Niwa, Eri Uemura, Yuki Matsuno, Hideki Taguchi. Translation-coupled protein folding assay using a protease to monitor the folding status., Protein Science, Vol. 28, No. 7, Page 1252-1261, July 2019.
• Frederic Deschoenmaeker, Shoko Mihara, Tatsuya Niwa, HIDEKI TAGUCHI, Jiro Nomata, Ken-Ichi Wakabayashi, TORU HISABORI. Disruption of the gene trx-m1 impedes the growth of Anabaena sp. PCC 7120 under nitrogen starvation, Plant and Cell Physiology (PCP), Apr. 2019.
• Nojima Tatsuya, Tatsuya Niwa, HIDEKI TAGUCHI. Proteome Analysis of Phase-Separated Condensed Proteins with Ionic Surfactants Revealed Versatile Formation of Artificial Bio-molecular Condensates, Biomacromolecules, Dec. 2018.  公式リンク  
  
• Frederic Deschoenmaeker, Shoko Mihara, Tatsuya Niwa, HIDEKI TAGUCHI, Ken-Ichi Wakabayashi, TORU HISABORI. The absence of thioredoxin m1 and thioredoxin C in Anabaena sp. PCC 7120 leads to oxidative stress., Plant and Cell Physiology (PCP), Vol. 59, No. 12, pp. 2432-2441, Dec. 2018.  公式リンク  
  
• Sugita Saori, Watanabe Kumiko, Hashimoto Kana, Tatsuya Niwa, Uemura Eri, HIDEKI TAGUCHI, Watanabe Yo-hei. Electrostatic interactions between middle domain motif-1 and the AAA1 module of the bacterial ClpB chaperone are essential for protein disaggregation, The Journal of biological chemistry, Vol. 293, No. 50, pp. 19228-19239, Oct. 2018.  公式リンク  
  
• Uemura Eri, Tatsuya Niwa, Minami Shintaro, Takemoto Kazuhiro, Fukuchi Satoshi, Machida Kodai, Imataka Hiroaki, Ueda Takuya, Ota Motonori, Hideki Taguchi. Large-scale aggregation analysis of eukaryotic proteins reveals an involvement of intrinsically disordered regions in protein folding, Scientific reports, Vol. 8, No. 1, pp. 678, Jan. 2018.
• Kashiwagi D, Sim S, Tatsuya Niwa, HIDEKI TAGUCHI, Aida T. Protein Nanotube Selectively Cleavable with DNA: Supramolecular Polymerization of "DNA-Appended Molecular Chaperones", Journal of the American Chemical Society, Vol. 140, No. 1, pp. 26-29, Jan. 2018.  公式リンク  
  
• Fujiwara K, Sawamura T, Tatsuya Niwa, Deyama T, Nomura SM, HIDEKI TAGUCHI, Doi N. In vitro transcription-translation using bacterial genome as a template to reconstitute intracellular profile, Nucleic acids research, Vol. 45, No. 19, pp. 11449-11458, Nov. 2017.  公式リンク  
  
• Yuhei Chadani, Tatsuya Niwa, Takashi Izumi, Nobuyuki Sugata, Asuteka Nagao, Tsutomu Suzuki, Shinobu Chiba, Koreaki Ito, Hideki Taguchi. Intrinsic Ribosome Destabilization Underlies Translation and Provides an Organism with a Strategy of Environmental Sensing, Molecular cell, Vol. 68, No. 3, pp. 528-539.e5, Nov. 2017.
• Seunghyun Sim, Tatsuya Niwa, Aida Takuzo, HIDEKI TAGUCHI. Supramolecular Nanotube of Chaperonin GroEL: Length Control for Cellular Uptake Using Single-Ring GroEL Mutant as End-Capper, Journal of the American Chemical Society, Vol. 138, No. 35, pp. 11152-11155, Sept. 2016.  公式リンク  
  
• Chadani Yuhei, Tatsuya Niwa, Chiba Shinobu, HIDEKI TAGUCHI, Ito Koreaki. Integrated in vivo and in vitro nascent chain profiling reveals widespread translational pausing, Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 7, pp. E829-E838, Aug. 2016.  公式リンク  
  
• Tatsuya Niwa, Fujiwara Kei, HIDEKI TAGUCHI. Identification of novel in vivo obligate GroEL/ES substrates based on data from a cell-free proteomics approach, FEBS letters, Vol. 590, No. 2, pp. 251-257, Jan. 2016.  公式リンク  
  
• Tatsuya Niwa, Sasaki Yoshihiro, Uemura Eri, Nakamura Shugo, Akiyama Minato, Ando Mitsuru, Sawada Shinichi, Mukai Sada-atu, Ueda Takuya, HIDEKI TAGUCHI, Akiyoshi Kazunari. Comprehensive study of liposome-assisted synthesis of membrane proteins using a reconstituted cell-free translation system, Scientific reports, Vol. 5, pp. 18025, Dec. 2015.  公式リンク  
  
• Tatsuya Niwa, Sugimoto Ryota, Watanabe Lisa, Nakamura Shugo, Ueda Takuya, HIDEKI TAGUCHI. Large-scale analysis of macromolecular crowding effects on protein aggregation using a reconstituted cell-free translation system, Frontiers in microbiology, Vol. 6, pp. 1113, July 2015.  公式リンク  
  
• Sim Seunghyun, Miyajima Daigo, Tatsuya Niwa, HIDEKI TAGUCHI, Aida Takuzo. Tailoring Micrometer-Long High-Integrity 1D Array of Superparamagnetic Nanoparticles in a Nanotubular Protein Jacket and Its Lateral Magnetic Assembling Behavior, Journal of the American Chemical Society, Vol. 137, No. 14, pp. 4658-4661, Apr. 2015.  公式リンク  
  
• Okuda Momoko, Tatsuya Niwa, HIDEKI TAGUCHI. Single-molecule Analyses of the Dynamics of Heat Shock Protein 104 (Hsp104) and Protein Aggregates, Journal of Biological Chemistry, Vol. 290, No. 12, pp. 7833-7840, Mar. 2015.  公式リンク  
  
• Ishimoto Takuya, Fujiwara Kei, Tatsuya Niwa, HIDEKI TAGUCHI. Conversion of a chaperonin GroEL-independent protein into an obligate substrate, Journal of Biological Chemistry, Vol. 289, No. 46, pp. 32073-32080, Nov. 2014.  公式リンク  
  
• Biswas Shuvendu, Kinbara Kazushi, Tatsuya Niwa, HIDEKI TAGUCHI, Ishii Noriyuki, Watanabe Sumiyo, Miyata Kanjiro, Kataoka Kazunori, Aida Takuzo. Biomolecular robotics for chemomechanically driven guest delivery fuelled by intracellular ATP, Nature chemistry, Vol. 5, No. 7, pp. 613-620, July 2013.  公式リンク  
  
• Tatsuya Niwa, Kanamori Takashi, Ueda Takuya, HIDEKI TAGUCHI. Global analysis of chaperone effects using a reconstituted cell-free translation system, Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 23, pp. 8937-8942, June 2012.  公式リンク  
  
• Sasaki Yoshihiro, Asayama Wakiko, Tatsuya Niwa, Sawada Shin-ichi, Ueda Takuya, Akiyoshi Kazunari, HIDEKI TAGUCHI. Amphiphilic polysaccharide nanogels as artificial chaperones in cell-free protein synthesis, Macromolecular bioscience, Vol. 11, No. 6, pp. 814-820, June 2011.  公式リンク  
  
• Takemoto Kazuhiro, Tatsuya Niwa, HIDEKI TAGUCHI. Difference in the distribution pattern of substrate enzymes in the metabolic network of Escherichia coli, according to chaperonin requirement, BMC systems biology, Vol. 5, pp. 98, June 2011.  公式リンク  
  
• Tatsuya Niwa, Bei-Wen Ying, Katsuyo Saito, WenZhen Jin, Shoji Takada, Takuya Ueda, HIDEKI TAGUCHI. Bimodal protein solubility distribution revealed by an aggregation analysis of the entire ensemble of Escherichia coli proteins, Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 11, pp. 4201-4206, Mar. 2009.  公式リンク  
  

国内会議発表 (査読有り)

• John Clyde Co Soriano, Daiya Ohara, Keiji Hirota, Gen Kondoh, Tatsuya Niwa, Tetsuya Kadonosono, Shinae Kizaka-Kondoh. Identification of Surface Markers and Functional activities of MDSC-like Adherent Cells (MLAC), 第45回日本分子生物学会年会, Dec. 2022.
• 山川賢太郎, 古木隆生, 古田忠臣, 畑中理恵, 黄川田隆洋, 丹羽達也, 田口英樹, 古澤宏幸, 岡畑恵雄, 櫻井実. Group3LEAペプチドのタンパク質凝集抑制メカニズムに関する実験的研究, 低温生物工学会誌, vol. 59, no. 2, pp. 95-99, Oct. 2013.

国内会議発表 (査読なし・不明)

• 待井長敏, 畑島諒, 中村遥奈, 丹羽達也, 長澤竜樹, 二階堂雅人. 東アフリカ産シクリッドにおける肥大化した唇の分子実態解明, 日本進化学会第27回沼津大会, Aug. 2022.
• 伊達弘貴･Thuc Toan Pham･丹羽達也･田口英樹･上野隆史, PHAM Toan Thuc, 丹羽 達也, 田口 英樹, 上野 隆史. pH応答性伸縮タンパク質集合体の反応メカニズム, 第71回高分子学会年次大会, May 2022.
• 待井長敏, 畑島諒, 中村遥奈, 丹羽達也, 田口 英樹, 長澤竜樹, 二階堂雅人.. マルチオミクス解析で探る「シクリッドの唇肥大化」の平行進化メカニズム, 日本動物学会関東支部第74回大会, Mar. 2022.
• 橋本 匡浩, 三木 卓幸, 中井 太一, 丹羽 達也, 三原 久和. 細胞内で自己集合するペプチドタグ開発１：クラスター形成を伴う蛋白質間相互作用解析, Mar. 2022.
• 山口 鉄郎, 山川 賢太郎, 古木 隆生, 畑中 理恵, 古澤 宏幸, 丹羽 達也, 古田 忠臣, 黄川田 隆洋, 田口 英樹, 岡畑 惠雄, 櫻井 実. Analysis on the interaction between G3LEA proteins and other proteins by quartz crystal microbalance, 第52回日本生物物理学会大会, Sept. 2014.

その他の論文・著書など

• 丹羽達也, 上田 卓也, 田口 英樹. 大腸菌全タンパク質の凝集性とシャペロン効果の網羅的な解析, 生物物理, The Biophysical Society of Japan General Incorporated Association, Vol. 53, No. 6, pp. 309-312, Nov. 2013.
• 丹羽達也, 田口英樹. 網羅的解析から見えてきたタンパク質の凝集特性とシャペロンの役割, バイオサイエンスとインダストリー = Bioscience & industry, Vol. 70, No. 6, pp. 448-452, Nov. 2012.
• 丹羽達也, 上田卓也, 田口英樹. 大腸菌全蛋白質の網羅的な凝集の解析, 蛋白質核酸酵素, Vol. 54, No. 14, pp. 1870-1875, Nov. 2009.

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