Journal Paper

• Rikiya Imamura, Mizuki Saito, Mikio Shimada, Junya Kobayashi, Masamichi Ishiai, Yoshihisa Matsumoto. APTX acts in DNA double-strand break repair in a manner distinct from XRCC4, Journal of Radiation Research, Mar. 2023.
• Kaima Tsukada, Mikio Shimada, Rikiya Imamura, Kotaro Saikawa, Masamichi Ishiai, Yoshihisa Matsumoto. The FHA domain of PNKP is essential for its recruitment to DNA damage sites and maintenance of genome stability, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, ELSEVIER, Nov. 2020.  Official location  

International Conference (Reviewed)

• Mikio Shimada, Kaima Tsukada, Rikiya Imamura, Tomoko Miyake, Yoshihisa Matsumoto. Phosphorylation of PNKP T118 by CDK is required for ionizing radiation induced DNA single and double strand break repair, 17th International Congress for Radiation Research, Aug. 2024.
• Rikiya Imamura, Mizuki Saito, Mikio Shimada, Masamichi Ishiai, Yoshihisa Matsumoto. The Functional Analysis of Genetic Disease Factor APTX in DNA Double Strand Break Repair, International Symposium on Zero-Carbon Energy Systems, Jan. 2023.

Domestic Conference (Reviewed)

• Rikiya IMAMURA, Mizuki SAITO, Mikio SHIMADA, Yoshihisa MATSUMOTO. Replication-associated DNA single-strand breaks are the source of PARP inhibitor sensitivity in XRCC1-deficient cells, 日本放射線影響学会第66回大会, Nov. 2024.
• Shoya TADA, Mikio SHIMADA, Kaima TSUKADA, Ryoichi HIRAYAMA, Rikiya Imamura, Risa MITOYA1 Yoshihisa MATSUMOTO. Analysis of radiosensitization effect by the combination with PLK1 inhibition and heavy particle beam in p53 mutant cells, 日本放射線影響学会第66回大会, Nov. 2024.
• Mikio Shimada, Kaima Tsukada, Rikiya Imamura, Yoshihisa Matsumoto. DNA末端リン酸化脱リン酸化酵素PNKPの機能解析と放射線増感効果の検討, 日本放射線腫瘍学会 第60回生物部会学術大会, June 2023.
• Rikiya Imamura, Mizuki Saito, Mikio Shimada, Masamichi Ishiai, Yoshihisa Matsumoto. The role of hereditary disease factor APTX in DNA replication and replication stress, 日本放射線影響学会 第64回大会, Sept. 2021.
• Kaima Tsukada, Rikiya Imamura, Mizuki Saito, Masamichi Ishiai, Mikio Shimada, Yoshihisa Matsumoto. The role of polynucleotide kinase phosphatase (PNKP) in Okazaki fragment maturation during DNA replication, 日本放射線影響学会 第64回大会, Sept. 2021.
• Riho Kamimoto, Rikiya Imamura, Mikio Shimada, Yoshihisa Matsumoto. Function of Aprataxin (APTX) in DNA damage response and repair in human cells, 日本放射線影響学会 第64回大会, Sept. 2021.
• Kotaro Saikawa, Kaima Tsukada, Rikiya Imamura, Yoshihisa Matsumoto, Yoshihisa Matsumoto. The role of intrinsic disorder region in polynucleotide kinase phosphatase (PNKP) in the maintenance of genome and chromosome stability, 日本放射線影響学会 第63回大会, Oct. 2020.
• Kaima Tsukada, Rikiya Imamura, Mikio Shimada, Masamichi Ishiai, Yoshihisa Matsumoto. The regulatory mechanism of polynucleotide kinase phosphatase PNKP revealed by fluorescent live cell imaging, 日本放射線影響学会 第63回大会, Oct. 2020.
• 今村 力也, 塚田 海馬, 齋川 昴太郎, 島田 幹男, Yoshihisa Matsumoto. Establishment of PNKP-deficient cells and functional analysis of PNKP in DNA damage and replication stress, 日本放射線影響学会 第63回大会, Oct. 2020.
• Kaima Tsukada, Rikiya Imamura, 斎川 昴太郎, Mikio Shimada, Yoshihisa Matsumoto. DNA修復因子PNKPの新たな機能とシグナリング経路の解明, 第25回 DNA複製・組換え・修復ワークショップ, Nov. 2019.
• Rikiya Imamura, Kaima Tsukada, Kotaro Saikawa, MIkio Shimada, Yoshihisa Matsumoto. Analyzing the role of PNKP in DNA damage response, 日本放射線影響学会 第62回大会, Nov. 2019.
• Kaima Tsukada, Rikiya Imamura, Mikio Shimada, Yoshihisa Matsumoto. Identification of novel function of PNKP involved in DNA repair and cell cycle checkpoint, 日本放射線影響学会 第62回大会, Nov. 2019.
• Mikio Shimada, Kaima Tsukada, Rikiya Imamura, Tomoko Miyake, Matsumoto. Analysis of transcriptional regulation of DNA repair machinery and cell death genes in induced pluripotent stem cells, 日本放射線影響学会 第62回大会, Nov. 2019.
• Kaima Tsukada, Rikiya Imamura, Mikio Shimada, Yoshihisa Matsumoto. 細胞周期チェックポイント・DNA修復におけるPNKPの役割, 第92回 日本生化学会大会, Sept. 2019.
• Rikiya Imamura, Kaima Tsukada, 齊川 昴太郎, Mikio Shimada, Yoshihisa Matsumoto. DNA複製・損傷修復におけるPNKPの機能解析, 2019年度日本生化学会関東支部例会, June 2019.

Domestic Conference (Not reviewed / Unknown)

• Rikiya Imamura, Mizuki Saito, Mikio Shimada, Junya Kobayashi, Masamichi Ishiai, Yoshihisa Matsumoto. The Role of APTX in DNA double-strand break repair, Jan. 2023.
• Rikiya Imamura, Kaima Tsukada, Kohtaro Saikawa, Mikio Shimada, Yoshihisa Matsumoto. DNA損傷修復因子PNKPの細胞周期チェックポイントへの関与, 令和元年度 若手放射線生物学研究会 専門研究会, Sept. 2019.
• Nozomi Kagawa, Kaima Tsukada, Hisayo Tsuchiya, Rikiya Imamura, Mikio Shimada, Yoshihisa Matsumoto. iPS細胞における放射線照射後のDNA損傷応答に関与するリン酸化・脱リン酸化機構解析, 平成30年度若手放射線生物学研究会専門研究会, Sept. 2018.

Degree

• APTX複合体のDNA損傷修復における役割,  Outline,  Tokyo Institute of Technology, 
• APTX複合体のDNA損傷修復における役割,  Summary,  Tokyo Institute of Technology, 

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