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Publication List - Kaima Tsukada (53 entries)
Journal Paper
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Mikio Shimada,
Takumi Tokumiya,
Tomoko Miyake,
Kaima Tsukada,
Norie Kanzaki,
Hiromi Yanagihara,
Junya Kobayashi,
Yoshihisa Matsumoto.
Implication of E3 ligase RAD18 in UV-induced mutagenesis in human induced pluripotent stem cells and neuronal progenitor cells,
Journal of Radiation Research,
Vol. 64,
No. 2,
pp. 345-351,
Mar. 2023.
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Tsuchiya H,
Shimada M,
Tsukada K,
Meng Q,
Kobayashi J,
Matsumoto Y.
The role of DNA double-strand break repair through non-homologous end joining in the dose-rate effect in terms of clonogenic ability,
Radiation Protection Dosimetry,
2022.
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Anie Day D.C. Asa,
Rujira Wanotayan,
Mukesh Kumar Sharma,
Kaima Tsukada,
Mikio Shimada,
Yoshihisa Matsumoto.
Functional Analysis of XRCC4 Mutations in Reported Microcephaly and Growth Defect Patients in Termsof Radiosensitivity.,
Journal of Radiation Research,
Apr. 2021.
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Hisayo Tsuchiya,
Mikio Shimada,
Kaima Tsukada,
Qingmei Meng,
Junya Kobayashi,
Yoshihisa Matsumoto.
Diminished or inversed dose-rate effect on clonogenic ability in Ku-deficient rodent cells,
Journal of Radiation Research,
Vol. 62,
No. 2,
pp. 198-205,
Mar. 2021.
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Ann-Marie K. Shorrocks*,
Samuel E. Jones*,
Kaima Tsukada*,
Carl A. Morrow*,
Zoulikha Belblidia,
Johanna Shen,
Iolanda Vendrell,
Roman Fischer,
Benedikt M. Kessler,
Andrew N. Blackford.
The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks,
Nature Communications,
Vol. 12,
No. 1,
Jan. 2021.
Official location
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Kaima Tsukada,
Mikio Shimada,
Rikiya Imamura,
Kotaro Saikawa,
Masamichi Ishiai,
Yoshihisa Matsumoto.
The FHA domain of PNKP is essential for its recruitment to DNA damage sites and maintenance of genome stability,
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis,
ELSEVIER,
Nov. 2020.
Official location
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Kaima Tsukada,
Yoshihisa Matsumoto,
Mikio Shimada.
Linker region is required for efficient nuclear localization of polynucleotide kinase phosphatase,
PLOS ONE,
Sept. 2020.
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Mikio Shimada,
Kaima Tsukada,
tomoko miyake.
iPS細胞およびiPS細胞由来外胚葉組織(神経、皮膚)における放射線影響と遺伝子発現変化,
放射線生物研究,
Vol. 54,
No. 4,
pp. 266-280,
Dec. 2019.
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Mikio Shimada,
Kaima Tsukada,
Nozomi Kagawa,
Yoshihisa Matsumoto.
Reprogramming and differentiation-dependent transcriptional alteration of DNA damage response and apoptosis genes in human induced pluripotent stem cells.,
Journal of Radiation Research,
Oct. 2019.
International Conference (Reviewed)
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Mikio Shimada,
Kaima Tsukada,
Rikiya Imamura,
Tomoko Miyake,
Yoshihisa Matsumoto.
Phosphorylation of PNKP T118 by CDK is required for ionizing radiation induced DNA single and double strand break repair,
17th International Congress for Radiation Research,
Aug. 2023.
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Mikio Shimada,
Kaima Tsukada,
Tomoko MIyake,
Norie Kanzaki,
Hiromi Yanagihara,
Yoshihisa Matsumoto.
Transcriptional alteration of DNA damage response genes after ionizing radiation exposure in induced pluripotent stem cells,
Radiation Research Society 65th Annual International Meeting,
Nov. 2019.
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Mikio Shimada,
Kaima Tsukada,
Nozomi Kagawa,
Yoshihisa Matsumoto.
Analysis of mechanism of DNA repair machinery and cell death in induced pluripotent stem cells,
International Congress of Radiation Research 2019,
Aug. 2019.
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Kaima TSUKADA,
Mikio Shimada,
Yoshihisa Matsumoto.
Development of p53-based DNA Damage Response Visualization System,
The 6th International Education Forum on Environment and Energy Science,
Dec. 2017.
Domestic Conference (Reviewed)
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Shoya TADA,
Mikio SHIMADA,
Kaima TSUKADA,
Ryoichi HIRAYAMA,
Rikiya Imamura,
Risa MITOYA1 Yoshihisa MATSUMOTO.
Analysis of radiosensitization effect by the combination with PLK1 inhibition and heavy particle beam in p53 mutant cells,
日本放射線影響学会第66回大会,
Nov. 2023.
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Mikio Shimada,
Kaima Tsukada,
Rikiya Imamura,
Yoshihisa Matsumoto.
DNA末端リン酸化脱リン酸化酵素PNKPの機能解析と放射線増感効果の検討,
日本放射線腫瘍学会 第60回生物部会学術大会,
June 2023.
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Raito Muramatsu,
Kaima Tsukada,
西内 巧,
Mikio Shimada,
Yoshihisa Matsumoto.
Analysis of the phosphorylation mechanism of the C-terminus of XRCC4 in DNA double-strand break repair,
本原子力学会関東・甲越支部第21回若手研究者・技術者研究討論会,
Jan. 2023.
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Yumin Huang,
Kaima Tsukada,
Mikio Shimada,
Yasuhiro OSHIMA,
Tetsuya SAKASHITA,
Yoshihisa Matsumoto.
Development of HCT116 cell line with norepinephrine transporter expression for the study of meta-211At-astato-beenzylguanidine therapy,
日本放射線腫瘍学会第59回生物部会学術大会,
June 2022.
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Kaima Tsukada,
Rikiya Imamura,
Mizuki Saito,
Masamichi Ishiai,
Mikio Shimada,
Yoshihisa Matsumoto.
The role of polynucleotide kinase phosphatase (PNKP) in Okazaki fragment maturation during DNA replication,
日本放射線影響学会 第64回大会,
Sept. 2021.
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Mikio Shimada,
Kaima Tsukada,
Kotaro Saikawa,
Tomoko Miyake,
Ryoichi Hirayama,
Yoshihisa Matsumoto.
High LET irradiation induceds multipplar cell division in human induced pluripotent stem cells,
日本放射線影響学会 第64回大会,
Sept. 2021.
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Enkhbaatar Milai,
Yoshihisa Matsumoto,
Mikio Shimada,
Kaima Tsukada,
Tomoko Miyake.
Molecular characterization of radiation sensitivity and radiation response of liver cancer cells,
日本放射線影響学会 第64回大会,
Sept. 2021.
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Chaity Modak,
Kaima Tsukada,
Anie Day Asa,
Mikio Shimada,
Yoshihisa Matsumoto.
The function of XRCC4-like factor (XLF) in DNA double-strand break repair and V(D)J recombination in human lymphoblastoid TK6,
日本放射線影響学会 第64回大会,
Sept. 2021.
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Hisayo Tsuchiya,
Mikio Shimada,
Kaima Tsukada,
孟 慶梅,
Junya Kobayashi,
Yoshihisa Matsumoto.
DNA二重鎖修復タンパク質Ku欠損細胞における線量率効果,
日本放射線腫瘍学会生物部会第58回学術大会,
June 2021.
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Enkhbaatar Milai,
tomoko miyake,
Kaima Tsukada,
Mikio Shimada,
Yoshihisa Matsumoto.
Molecular characterization of radio-sensitivity of hepatocellular carcinoma,
日本放射線影響学会 第63回大会,
Oct. 2020.
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Kotaro Saikawa,
Kaima Tsukada,
Rikiya Imamura,
Yoshihisa Matsumoto,
Yoshihisa Matsumoto.
The role of intrinsic disorder region in polynucleotide kinase phosphatase (PNKP) in the maintenance of genome and chromosome stability,
日本放射線影響学会 第63回大会,
Oct. 2020.
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今村 力也,
塚田 海馬,
齋川 昴太郎,
島田 幹男,
Yoshihisa Matsumoto.
Establishment of PNKP-deficient cells and functional analysis of PNKP in DNA damage and replication stress,
日本放射線影響学会 第63回大会,
Oct. 2020.
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Kaima Tsukada,
Rikiya Imamura,
Mikio Shimada,
Masamichi Ishiai,
Yoshihisa Matsumoto.
The regulatory mechanism of polynucleotide kinase phosphatase PNKP revealed by fluorescent live cell imaging,
日本放射線影響学会 第63回大会,
Oct. 2020.
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Kaima Tsukada,
Rikiya Imamura,
斎川 昴太郎,
Mikio Shimada,
Yoshihisa Matsumoto.
DNA修復因子PNKPの新たな機能とシグナリング経路の解明,
第25回 DNA複製・組換え・修復ワークショップ,
Nov. 2019.
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Hisayo Tsuchiya,
Kaima Tsukada,
Mikio Shimada,
Matsumoto.
Involvement fo Ku protein in the dose rate effect,
日本放射線影響学会 第62回大会,
Nov. 2019.
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Mikio Shimada,
Kaima Tsukada,
Rikiya Imamura,
Tomoko Miyake,
Matsumoto.
Analysis of transcriptional regulation of DNA repair machinery and cell death genes in induced pluripotent stem cells,
日本放射線影響学会 第62回大会,
Nov. 2019.
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Kaima Tsukada,
Rikiya Imamura,
Mikio Shimada,
Yoshihisa Matsumoto.
Identification of novel function of PNKP involved in DNA repair and cell cycle checkpoint,
日本放射線影響学会 第62回大会,
Nov. 2019.
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Rikiya Imamura,
Kaima Tsukada,
Kotaro Saikawa,
MIkio Shimada,
Yoshihisa Matsumoto.
Analyzing the role of PNKP in DNA damage response,
日本放射線影響学会 第62回大会,
Nov. 2019.
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Kaima Tsukada,
Rikiya Imamura,
Mikio Shimada,
Yoshihisa Matsumoto.
細胞周期チェックポイント・DNA修復におけるPNKPの役割,
第92回 日本生化学会大会,
Sept. 2019.
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Mikio Shimada,
Kaima Tsukada,
tomoko miyake,
Yoshihisa Matsumoto.
ヒトiPS細胞における放射線依存的なDNA損傷と分子修復機構の解析,
第92回 日本生化学会大会,
Sept. 2019.
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Kaima Tsukada,
Carl Morrow,
Mikio Shimada,
Yoshihisa Matsumoto,
Andrew N Blackford.
BLM遺伝子が制御するDNA損傷修復機構,
第56回 アイソトープ・放射線研究発表会,
July 2019.
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Rikiya Imamura,
Kaima Tsukada,
齊川 昴太郎,
Mikio Shimada,
Yoshihisa Matsumoto.
DNA複製・損傷修復におけるPNKPの機能解析,
2019年度日本生化学会関東支部例会,
June 2019.
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Mikio Shimada,
Kaima Tsukada,
Nozomi Kagawa,
Yoshihisa Matsumoto.
iPS細胞における放射線照射による遺伝子発現制御と細胞死への影響,
日本放射線影響学会第61回大会,
Nov. 2018.
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Nozomi Kagawa,
Kaima Tsukada,
Hisayo Tsuchiya,
Mikio Shimada,
Yoshihisa Matsumoto.
iPS細胞におけるゲノム安定性維持に関わるリン酸化・脱リン酸化機構解析,
日本放射線影響学会第61回大会,
Nov. 2018.
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Hisayo Tsuchiya,
Kaima Tsukada,
Nozomi Kagawa,
Mikio Shimada,
Yoshihisa Matsumoto.
ヒト多能性幹細胞における放射線照射後のDNA損傷応答とアポトーシスの解析,
日本放射線影響学会第61回大会,
Nov. 2018.
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Mikio Shimada,
Naoya Kase,
Kaima Tsukada,
Yoshihisa Matsumoto.
iPS細胞における放射線応答機構と細胞周期チェックポイントの解析,
日本放射線影響学会第60回大会,
Oct. 2017.
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Kaima Tsukada,
Mikio Shimada,
Yoshihisa Matsumoto.
DNA損傷応答可視化へ向けたGFP-p53融合タンパク質の発現と挙動の解析,
日本放射線影響学会第60回大会,
Oct. 2017.
International Conference (Not reviewed / Unknown)
Domestic Conference (Not reviewed / Unknown)
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Kaima Tsukada,
Morrow Carl,
Mikio Shimada,
Yoshihisa Matsumoto,
Blackford Andrew.
BLMヘリカーゼが司るDNA損傷修復とゲノム安定性維持機構,
令和元年度 若手放射線生物学研究会 専門研究会,
Sept. 2019.
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Rikiya Imamura,
Kaima Tsukada,
Kohtaro Saikawa,
Mikio Shimada,
Yoshihisa Matsumoto.
DNA損傷修復因子PNKPの細胞周期チェックポイントへの関与,
令和元年度 若手放射線生物学研究会 専門研究会,
Sept. 2019.
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Nozomi Kagawa,
Kaima Tsukada,
Hisayo Tsuchiya,
Rikiya Imamura,
Mikio Shimada,
Yoshihisa Matsumoto.
iPS細胞における放射線照射後のDNA損傷応答に関与するリン酸化・脱リン酸化機構解析,
平成30年度若手放射線生物学研究会専門研究会,
Sept. 2018.
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Mikio Shimada,
Kaima Tsukada,
Nozomi Kagawa,
Yoshihisa Matsumoto.
iPS細胞における遺伝子発現変動と放射線照射による細胞死への影響,
平成30年度若手放射線生物学研究会専門研究会,
Sept. 2018.
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Kaima Tsukada,
Mikio Shimada,
Yoshihisa Matsumoto.
ヒト細胞内におけるGFP-p53融合タンパク質を利用したDNA損傷応答可視化システム,
2017年度生命科学系学会合同年次大会,
Dec. 2017.
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Kaima Tsukada,
Mikio Shimada,
Yoshihisa Matsumoto.
生体内でのDNA損傷応答可視化に向けたGFP-p53融合タンパク質の発現・挙動解析,
平成29年度若手放射線生物学研究会専門研究会,
Sept. 2017.
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Kaima Tsukada,
Mikio Shimada,
Yoshihisa Matsumoto.
ヒト細胞でのGFP-p53融合タンパク質の発現とDNA損傷応答の解析,
平成29年度日本生化学会関東支部例会,
June 2017.
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Kaima Tsukada,
Mikio Shimada,
Yoshihisa Matsumoto.
p53制御機構を利用したDNA損傷応答インディケーターシステム,
第56回日本生体医工学会,
May 2017.
Degree
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DNA修復におけるDNAリン酸化・脱リン酸化酵素PNKPの制御機構,
Summary,
Doctor (Science),
Tokyo Institute of Technology,
2021/03/26,
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DNA修復におけるDNAリン酸化・脱リン酸化酵素PNKPの制御機構,
Exam Summary,
Doctor (Science),
Tokyo Institute of Technology,
2021/03/26,
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DNA修復におけるDNAリン酸化・脱リン酸化酵素PNKPの制御機構,
Outline,
Doctor (Science),
Tokyo Institute of Technology,
2021/03/26,
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DNA修復におけるDNAリン酸化・脱リン酸化酵素PNKPの制御機構,
Thesis,
Doctor (Science),
Tokyo Institute of Technology,
2021/03/26,
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