論文

• Ito Y, Hirose M, Tokunaga M. Slitflow: A Python framework for single- molecule dynamics and localization analysis., SoftwareX, Vol. 23, No. 101462, Page 6, June 2023.
• Yuma Ito, Masanori Hirose, Makio Tokunaga. Slitflow: a Python framework for single-molecule dynamics and localization analysis, bioRxiv, Mar. 2023.  公式リンク  
  
• Matsumori H, Watanabe K, Tachiwana H, Fujita T, Ito Y, Tokunaga M, Sakata-Sogawa K, Osakada H, Haraguchi T, Awazu A, Ochiai H, Sakata Y, Ochiai K, Toki T, Ito E, Goldberg IG, Tokunaga K, Nakao M, Saitoh N. Ribosomal protein L5 facilitates rDNA-bundled condensate and nucleolar assembly, Life Sci Alliance, Vol. 5, No. 7, p. e202101045, Mar. 2022.  公式リンク  
  
• Uchino S, Ito Y, Sato Y, Handa T, Ohkawa Y, Tokunaga M, Kimura H. Live imaging of transcription sites using an elongating RNA polymerase II-specific probe., J Cell Biol, Vol. 221, No. 2, p. e202104134 (23 pages), Dec. 2021.  公式リンク  
  
• Yang Liu, Ning Zhao, Masato T. Kanemaki, Yotaro Yamamoto, Yoshifusa Sadamura, Yuma Ito, Makio Tokunaga, Timothy J. Stasevich, Hiroshi Kimura. Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells, Genes Cells., Vol. 26, No. 11, p. 905-926, Sept. 2021.  公式リンク  
  
• Uchino S, Ito Y, Sato Y, Handa T, Yasuyuki Ohkawa, Tokunaga M, Kimura H. Visualizing transcription sites in living cells using a genetically encoded probe specific for the elongating form of RNA polymerase II, bioRxiv, No. 2021.04.27, p. 441582, Apr. 2021.  公式リンク  
  
• Lim Wei Ming, Ito Y, Sakata-Sogawa K, Tokunaga M. CLIP-170 is essential for MTOC repositioning during T cell activation by regulating dynein localisation on the cell surface, Scientific Reports, Vol. 8, No. 1, p. 17447, Nov. 2018.
• Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. Multi-color single-molecule tracking and subtrajectory analysis for quantification of spatiotemporal dynamics and kinetics upon T cell activation., Scientific Reports, Vol. 7, No. 1, p. 6994, Aug. 2017.
• Chanyoung Shin, Yuma Ito, Shota Ichikawa, Makio Tokunaga, Kumiko Sakata-Sogawa, Takashi Tanaka. MKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses., Scientific Reports, Vol. 7, p. 46097, Apr. 2017.
• Shuya Kasai, Shinji Kajimoto, Yuma Ito, Tomo Saito, Kenichi Yasumoto, Tokunaga M, Sakata-Sogawa K, Hiroshi Fukumura, Kazuhiro Sogawa. Conformational changes in inhibitory PAS domain protein associated with binding of HIF-1α and Bcl-xL in living cells.,  Journal of Biochemistry, Vol. 161, No. 3, p. 291-296, Mar. 2017.
• Yamazaki Shota, Hiroshi Yamamoto, Makio Tokunaga, Kumiko Sakata-Sogawa, Masahiko Harada. Nuclear actin activates human transcription factor genes including the OCT4 gene, Biosci Biotechnol Biochem, Vol. 79, No. 2, p. 242-246, Feb. 2015.
• Timothy J. Stasevich, Yoko Hayashi-Takanaka, Yuko Sato, Kazumitsu Maehara, Yasuyuki Ohkawa, Kumiko Sakata-Sogawa, Makio Tokunaga, Takahiro Nagase, Naohito Nozaki, James G. McNally, Hiroshi Kimura. Regulation of RNA polymerase II activation by histone acetylation in single living cells, Nature, vol. 516, No. 7530, pp. 272-275, Dec. 2014.
• Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. A Facile Preparation of Glass-supported Lipid Bilayers for Analyzing Molecular Dynamics, Anal Sci, Vol. 30, No. 12, p. 1103-1106, Dec. 2014.  公式リンク  
  
• Asakawa H, Yang HJ, Yamamoto TG, Ohtsuki C, Chikashige Y, Sakata-sogawa K, Tokunaga M, Iwamoto M, Hiraoka Y, Haraguchi T. Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe, Nulceus, Vol. 5, No. 2, p. 149-162, Mar. 2014.
• Kentaro Hotta, Akihiro Nashimoto, Eiji Yasumura, Masafumi Suzuki, Motoki Azuma, Yosuke Iizumi, Daisuke Shima, Ryusuke Nabeshima, Masaki Hiramoto, Akira Okada, Kumiko Sakata-Sogawa, Makio Tokunaga, Takumi Ito, Hideki Ando, Satoshi Sakamoto, Yasuaki Kabe, Shinichi Aizawa, Takeshi Imai, Yuki Yamaguchi, Hajime Watanabe, Hiroshi Handa. Vesnarinone suppresses TNFα mRNA expression by inhibiting valosin-containing protein, Mol. Pharmacol., Vol. 83, No. 5, pp. 930-938, May 2013.
• Hashimoto-Tane A, Yokosuka T, Sakata-Sogawa K, Sakurma M, Ishihara, C, Tokunaga M, Saito T. Dynein-driven transport of T cell receptor mictoclusters forms the xSMAC and regulates T cell activation, Immunity, Vol. 34, No. 6, p. 919-931, June 2011.
• Tadashi Yokosuka, Wakana Kobayashi, Masako Takamatsu, Kumiko Sakata-Sogawa, Hu Zeng, Akiko Hashimoto-Tane, Hideo Yagita, Makio Tokunaga, Takashi Saito. Spatiotemporal Basis of CTLA-4 Costimulatory Molecule-Mediated Negative Regulation of T Cell Activation, Immunity, Vol. 33, pp. 326-339, Sept. 2010.
• Nobuyuki Shiina, Kazuhiko Yamaguchi, Makio Tokunaga. RNG105 Deficiency Impairs the Dendritic Localization of mRNAs for Na/K ATPase Subunit Isoforms and Leads to the Degeneration of Neuronal Networks., The Journal of Neuroscience, Vol. 30, No. 38, pp. 12816 –12830, Sept. 2010.
• Shiina N, Tokunaga M. RNA Granule Protein 140 (RNG140): A Paralog of RNG105 Localized to Distinct RNA Granules in Neuronal Dendrites in the Adult Vertebrate Brain., J. Biol. Chem., Vol. 285, No. 31, pp. 24260-24269, July 2010.
• Ana V. Miletic, Daniel B. Graham, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J. Hamann, Saso Cemerski, Tracie Kloeppel, Daniel D. Billadeau, Osami Kanagawa, Makio Tokunaga, Wojciech Swat. Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity., PLoS One, Vol. 4, No. 8, e6599, Aug. 2009.
• Akihiro FUKAGAWA, Michio HIROSHIMA, Isao SAKANE, Makio TOKUNAGA. Direct Observation of Multiple and Stochastic Transition States by a Feedback-controlled Single-molecule Force Measurement, ANALYTICAL SCIENCES, Vol. 25, No. 1, pp. 5-7, Jan. 2009.
• Akihiro Fukagawa, Michio Hiroshima, Isao Sakane, Makio Tokunaga. Stochastic emergence of multiple intermediates detected by single-molecule quasi-static mechanical unfolding of protein, BIOPHYSICS, THE BIOPHYSICAL SOCIETY OF JAPAN, Vol. 5, pp. 25-35, 2009.
• Tadashi Yokosuka, Wakana Kobayashi, Kumiko Sakata-Sogawa, Masako Takamatsu, Akiko Hashimoto-Tane, Michael L. Dustin, Makio Tokunaga, Takashi Saito. Spatiotemporal Regulation of T Cell Costimulation by TCR-CD28 Microclusters and Protein Kinase C θ Translocation, Immunity, Cellpress, Volume 29, Number 4, pp. 589-601, Oct. 2008.
• Makio Tokunaga, Naoko Imamoto, Kumiko Sakata-Sogawa. Highly inclined thin illumination enables clear single-molecule imaging in cells, Nature methods, nature publishing group, volume 5, number 2, pp. 159-161, Feb. 2008.
• Satoru Yamasaki, Kumiko Sakata-Sogawa, Aiko Hasegawa, Tomoyuki Suzuki, Koki Kabu, Emi Sato, Satoru Yamasaki, Aiko Hasegawa, Tomoyuki Suzuki, Koki Kabu, Emi Sato, Tomohiro Kurosaki, Susumu Yamashita, Makio Tokunaga, Keigo Nishida, Toshio Hirano. Zinc is a novel intracellular second messenger, THE JOURNAL OF CELL BIOLOGY, Vol. 177, No. 4, pp. 637-645, May 2007.
• Ana V. Miletic, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J. Hamann, Timothy S. Gomez, Naruhisa Ota, Tracie Kloeppel, Osami Kanagawa, Makio Tokunaga, Daniel D. Billadeau, Wojciech Swat. Vav1 Acidic Region Tyrosine 174 Is Required for the Formation of T Cell Receptor-induced Microclusters and Is Essential in T Cell Development and Activation, J Biol Chem., Vol. 281, No. 50, pp. 38257-38265, Dec. 2006.
• Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Koji Ogata, Kumiko Sakata-Sogawa, Michio Hiroshima, David L Wiest, Makio Tokunaga, Takashi Saito. Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development, nature immunology, volume 7, number 1, pp. 67-75, Feb. 2006.
• Tadashi Yokosuka, Kumiko Sakata-Sogawa, Wakana Kobayashi, Michio Hiroshima, Akiko Hashimoto-Tane, Makio Tokunaga, Michael L Dustin, Takashi Saito. Newly generated T cell receptor microclusters initiate and sustain T cell activaion by recruitment of Zap70 and SLP-76, nature immunology, volume 6, number 12, pp. 1253-1262, Dec. 2005.
• Nobuyuki Shiina, Kazumi Shinkura, Makio Tokunaga. A Novel RNA-Binding Protein in Neuronal RNA Granules:Regulatory Machinery for Local Translation, The Journal of Neuroscience, Vol. 25, No. 17, pp. 4420-4434, Apr. 2005.
• Kazuo Kitamura, Makio Tokunaga, Seiji Esaki, Atsuko Hikikoshi Iwane, Toshio Yanagida. Mechanism of muscle contraction based on stochastic properties of single actomyosin motors observed in vitro, BIOPHYSICS, Vol. 1, pp. 1-19, 2005.
• Yasuyuki Hirakawa, Masashi Suzuto, Hitoshi Ohnishi, Tomoteru Shingaki, Edward M. Eyring, Makio Tokunaga, Tsutomu Masujima. Observation and analysis of single DNA nano-kinetics by pin-fiber video scope, The ANALYST, Vol. 128, No. 6, pp. 676-680, June 2003.
• Yasuyuki HIRAKAWA, Masashi SUZUTOH, Hitoshi OHNISHI, Tomoteru SHINGAKI, Edward M. EYRING, Makio TOKUNAGA, Tsutomu MASUJIMA. Analysis of the Nano-Kinetic Movement of a Single DNA by a Pin-Fiber Video Scope, ANALYTICAL SCIENCES, Vol. 18, No. 12, pp. 1293-1294, Dec. 2002.
• ATSUSHI FUKUZAWA, MICHIO HIROSHIMA, KOSCAK MARUYAMA, NAOTO YONEZAWA, MAKIO TOKUNAGA, SUMIKO KIMURA. Single-molecule measurement of elasticity of Serine-, Glutamate- and Lysine-Rich repeats of invertebrate connectin reveals that its elasticity is caused entropically by random coil structure, Journal of Muscle Research and Cell Motility, Kluwer Academic Publishers, Vol. 23, No. 5-6, pp. 449–453, 2002.
• Kazuo Kitamura, Akihiko Ishijima, Makio Tokunaga, Toshio Yanagida. Single-Molecule Nanobiotechnology, JSAP International, No. 4, pp. 4-9, June 2001.
• Takaaki Aoki, Yoshiyuki Sowa, Hiroaki Yokota, Michio Hiroshima, Makio Tokunaga, Yoshiharu Ishii, Toshio Yanagida. Non-Contact Electrostatic Surface Force Imaging of Single Protein Filaments using Intermolecular Force Microscopy, Single Moledules, Vol. 2, pp. 183-190, 2001.
• T. Yanagida, S. Esaki, A. Hikikoshi Iwane, Y. Inoue, A. Ishijima, K. Kitamura, H. Tanaka, M. Tokunaga. Single-motor mechanics and models of the myosin motor, Phil. Trans. R. Soc. Lond. B, THE ROYAL SOCIETY, Vol. 355, No. 1396, pp. 441-447, Apr. 2000.
• Kazuo Kitamura, Makio Tokunaga, Atsuko Hikikoshi Iwane, Toshio Yanagida. A single myosin head moves along an actin filament with regular steps of 5.3 nanometres, nature, Vol. 397, No. 6715, pp. 129-134, Jan. 1999.
• Akihiko Ishijima, Hiroaki Kojima, Takashi Funatsu, Makio Tokunaga, Hideo Higuchi, Hiroto Tanaka, Toshio Yanagida. Simultaneous Observation of Individual ATPase and Mechanical Events by a Single Myosin Molecule during Interaction with Actin, Cell, Vol. 92, No. 2, pp. 161-171, Jan. 1998.
• Yoshie Harada, Takashi Funatsu, Makio Tokunaga, Kiwamu Saito, Hideo Higuchi, Yoshiharu Ishii, Toshio Yanagida. Single Molecule Imaging and Nanomanipulation of Biomolecules, METHODS IN CELL BIOLOGY, Vol. 55, pp. 117-128, 1998.
• K. SAITO, M. TOKUNAGA, A. H. IWANE, T. YANAGIDA. Dual-colour microscopy of single fluorophores bound to myosin interacting with fluorescently labelled actin using anti-Stokes fluorescence, Journal of Microscopy, Vol. 188, No. 3, pp. 255-263, Dec. 1997.
• Makio Tokunaga, Kazuo Kitamura, Kiwamu Saito, Atsuko Hikikoshi Iwane, Toshio Yanagida. Single Molecule Imaging of Fluorophores and Enzymatic Reactions Achieved by Objective-Type Total Internal Reflection Fluorescence Microscopy, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Academic Press, Vol. 235, No. 1, pp. 47-53, Dec. 1997.
• Takashi Funatsu, Yoshie harada, Hideo Higuchi, Makio Tokunaga, Kiwamu Saito, Yoshiharu Ishii, Ronald D. Vale, Toshio Yanagida. Imaging and nano-manipulation of single biomolecules, Biophysical Chemistry, Vol. 68, pp. 63-72, Oct. 1997.
• Atsuko Hikikoshi Iwane, Takashi Funatsu, Yoshie Harada, Makio Tokunaga, Osamu Ohara, Sayuri Morimoto, Toshio Yanagida. Single molecular assay of individual ATP turnover by a myosin-GFP fusion protein expressed in vitro, FEBS, Vol. 407, No. 2, pp. 235-238, Apr. 1997.
• Makio Tokunaga, Takaaki Aoki, Michio Hiroshima, Kazuo Kitamura, Toshio Yanagida. Subpiconewton Intermolecular Force Microscopy, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Academic Press, Vol. 231, No. 3, pp. 566-569, Feb. 1997.
• Atsuko Hikikoshi Iwane, Kazuo Kitamura, Makio Tokunaga, Toshio Yanagida. Myosin Subfragment-1 Is Fully Equipped with Factors Essential for Motor Function, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol. 230, No. 1, pp. 76-80, Jan. 1997.
• Takaaki Aoki, Michio Hiroshima, Kazuo Kitamura, Makio Tokunaga, Toshio Yanagida. Non-contact scanning probe microscopy with sub-piconewton force sensitivity, ultramicroscopy, Vol. 70, pp. 45-55, 1997.
• Yasunobu Sugimoto, Makio Tokunaga, Yasunori Takezawa, Mitsuo Ikebe, Katsuzo Wakabayashi. Conformational Changes of the Myosin Heads during Hydrolysis of ATP as Analyzed by X-Ray Solution Scattering, Biophysical Journal, the Biophysical Society, Vol. 68, No. 4, pp. 29-34, Apr. 1995.
• Takashi Funatsu, Yoshie Harada, Makio Tokunaga, Kiwamu Saito, Toshio Yanagida. Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution, NATURE, Vol. 374, No. 6522, pp. 555-559, Apr. 1995.
• Makio Tokunaga, Katsuzo Wakabayashi, Yasunobu Sugimoto, Toshiaki Hamanaka, Takeyuki Wakabayashi. Structural change of the myosin head detected by electron microscopy and small-angle X-ray scattering., Synchrotron Radiation in the Biosciences, Oxford University Press, pp. 493-501, 1994.
• Katsuzo Wakabayashi, Makio Tokunaga, Izumi Kohno, Yasunobu Sugimoto, Toshiaki Hamanaka, Yasunori Takezawa, Takeyuki Wakabayashi, Yoshiyuki Amemiya. Small-Angle Synchrotron X-ray Scattering Reveals Distinct Shape Changes of the Myosin Head During Hydrolysis of ATP, Science, Vol. 258, pp. 443-447, Oct. 1992.
• MAKIO TOKUNAGA, KAZUO SUTHO, TAKEYUKI WAKABAYASHI. STRUCTURE AND STRUCTURAL CHANGE OF THE MYOSIN HEAD, Adv. Biophys, Vol. 27, pp. 157-167, 1991.
• Kimiko Saeki, Makio Tokunaga, Hian Ann Ting, Takeyuki Wakabayashi. New Method to Prepare Single-Headed Heavy Meromyosin with High Purity and a High Yield, J. Biochem, Vol. 106, pp. 606-611, Oct. 1989.
• Kazuo Sutoh, Makio Tokunaga, Takeyuki Wakabayashi. Electron Microscopic Mappings of Myosin Head with Site-directed Antibodies, J. Mol. Biol, Vol. 206, No. 2, pp. 357-363, 1989.
• Wakabayashi T, Akiba T, Hirose K, Tomioka A, Tokunaga M, Suzuki M, Toyoshima C, Sutoh K, Yamamoto K, Matsumoto T. Temperature-induced change of thick filament and location of the functional sites of myosin, Adv.Exp.Med.Biol, No. 226, p. 39-48, 1988.
• Makio Tokunaga, Kazuo Sutoh, Chikashi Toyoshima, Takeyuki Wakabayashi. Location of the ATPase site of myosin determined by three-dimensional electron microscopy, Nature, Macmillan Journals Ltd, Vol. 329, No. 6140, pp. 635-638, Oct. 1987.
• Kazuo Sutoh, Makio Tokunaga, Takeyuki Wakabayashi. Electron Microscopic Visualization of the N Terminusof the Myosin Heavy Chain using a Site-directed Antibody, J. MOl. Biol., Academic Press Inc., Vol. 195, No. 4, pp. 953-956, June 1987.
• Makio Tokunaga, Masashi Suzuki, Kimiko Saeki, Takeyuki Wakabayashi. Position of the Amino Terminus of Myosin Light Chain 1 and Light Chain 2 Determined by Electron Microscopy with Monoclonal Antibody, J. Mol. Biol., Vol. 194, No. 2, pp. 245-255, May 1987.
• Masaki Suzuki, Kimiko Saeki, Makio Tokunaga, Takeyuki Wakabayashi. Monoclonal Antibody which Recognizes Trimethylated N-Terminus of Histone H2B, Proc. Japan Adad., Vol. 63, No. Ser.B, pp. 385-388, 1987.
• Keiichi Yamamoto, Makio Tokunaga, Kazuo Sutoh, Takeyuki Wakabayashi, Takamitsu Sekine. Location of the SH Group of the Alkali Light Chain on the Myosin Head as Revealed by Eklectron Microscopy, J. Mol. Biol., Vol. 2, No. 183, pp. 257-290, May 1985.
• Takeyuki Wakabayashi, Akihiro Tomioka, Makio Tokunaga, Masasuke Yoshida, Yasuo Kagawa, Jiro Usukura, Eichi Yamada. Image analysis of electron micrographs of ATPase (Coupling Factor TF1) from thermophilic bacteria and luminal epithelium of mouse urinary bladder., Tokai J Exp Clin Med, Vol. 7, Supplement, pp. 15-22, July 1982.

著書

• 伊藤由馬, 徳永万喜洋. 生細胞内の１分子動態と相互作用の定量解析, パリティ "特集：物理科学、この一年", 丸善, Vol. 34, No. 1, p. 72-74, Jan. 2019.  公式リンク  
• 徳永万喜洋, 伊藤由馬. 全反射照明蛍光顕微鏡 ― 対物レンズ型, “生きてるものは全部観る! イメージングの選び方・使い方100＋”, 実験医学2018年12月増刊号, 羊土社, Vol. 36, No. 20, p. 36-38, Dec. 2018.
• 徳永万喜洋, 十川久美子. 全反射照明蛍光顕微鏡, 第４版 現代界面コロイド化学の基礎, No. 8, pp. 433-436, May 2018.
• 徳永 万喜洋. １分子操作, １分子生物学, 化学同人, No. 17, 215-227, Oct. 2014.
• 徳永万喜洋, 日本生物物理学会. 分子でできた究極の微小モーター, 新生物物理の最前線, 講談社ブルーバックス, Apr. 2010.
• 半田宏, 伊藤武彦, 岩崎博史, 岡田典弘, 岸本健雄, 工藤明, 白髭克彦, 田中幹子, 徳永万喜洋, 広瀬茂久, 村上聡, 菊池韶彦. ハートウェル遺伝学-遺伝子、ゲノム、そして生命システムへ-, メディカルサイエンスインターナショナル, Mar. 2010.
• 徳永万喜洋, 十川久美子. 全反射照明蛍光顕微鏡(TIRF), 第３版 現代界面コロイド化学の基礎, 丸善, pp. 399-401, Apr. 2009.
• 徳永万喜洋. アクチン・ミオシンモーター系, 生物物理学ハンドブック, 朝倉書店, pp. 343-347, Apr. 2007.
• 徳永万喜洋. 分子モーター, 物理学大辞典, 朝倉書店, pp. 766-775, Oct. 2005.
• 徳永万喜洋. 表面のみを高画質に観察できる全反射蛍光顕微鏡法, バイオイメージングでここまで理解る, 羊土社, pp. 104-113, Apr. 2002.
• 徳永万喜洋, 日本生物物理学会. ゆらぎで働くメカニズム－生物らしい分子モーター機能とは－, 吉岡書店, pp. 130-157, 1997.

国際会議発表 (査読有り)

• Satoshi Uchino, Yuma Ito, Jessica Dai, Yuko Sato, Tetsuya Handa, Yasuyuki Ohkawa, Makio Tokunaga, Hiroshi Kimura. Live imaging of the initiation and elongation forms of RNA polymerase II using phosphorylation-specific probes., The 30th Hot Spring Harbor International Symposium(Online), Jan. 2022.
• Yamasaki S, Sakata-Sogawa K, Hasegawa A, Suzuki T, Kabu K, Sato E, Kurosaki T, Yamashita S, Tokunaga M, Nishida K, Hirano T. Zinc is a novel intracellular second messenger., 1st meeting of the Society for Zinc Biology,, Feb. 2017.
• Kumiko Sakata-Sogawa, Yuma Ito, Makio Tokunaga. Integrated imaging approach of transcription regulatory proteins in living cells, UK/RoI-Japan Symposium on frontier technologies “From single molecules to cells and tissues”, July 2016.
• Ito Y, Harata M, Kimura K, Sakata-Sogawa K, Tokunaga M. Dynamics of INO80 Chromatin Remodeling Complex by Live-cell Molecular Imaging., International Symposium on Chromatin Structure, Dynamics, and Function, Aug. 2015.
• Brian P.English, Tatsuya Morisaki, Kumiko Sakata-Sogawa, Makio Tokunaga, Naohito Nozaki, Hiroshi Kimura, Timothee Lionnet Timothy J.Stasevich. Towards Single-Gene Imaging of Endogenous Histone and RNA Polumerase ⅡModifications in Living Cells, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Yuma Ito, Hiroshi Kimura, Hitoshi Kurumizaka, Masahiko Harada, Kumiko Sakata-Sogawa, Makio Tokunaga. Integrated Imaging Approach to the Study of Chromatin Dynamics, International Symposium on Chromatin Structure Dynamics,and Function, 2015.
• Shota Yamazaki, Koji Yamamoto, Kumiko Sakata-Sogawa, Makio Tokunaga, Masahiko Harata. Roles of nuclear filamentous-actin in transcriptional regulation., 2014 ASCB/IFCB Meeting (The American Society for Cell Biology / International Federation for Cell Biology), Dec. 2014.
• Ito Y, Inaba N, Harata M, Kimura H, Tokunaga M, Sakata-Sogawa K.. Quantitative imaging analysis of molecular dynamics of actin- related protein in the nucleus., 58th Annual Meeting of Biophysical Society, Feb. 2014.
• Tokunaga M., Fukagawa A., Sakata-Sogawa K.. Single molecule imaging in living cells and stochastic features of inter- and intra-molecular interactions., The 10th NIBB-EMBL Symposium 2013 “Quantitative Bioimaging”, Mar. 2013.
• Tokunaga M., Fukagawa A., Sakata-Sogawa K. Single molecule imaging in living cells and stochastic features of inter- and intra-molecular interactions, 1st Bioscience and Biotechnology International symposium “Biomolecular assemblies from nano to micro”, Jan. 2013.
• Ito Y., Sakata-Sogawa K., Tokunaga M.. Development of stimulatory lipid bilayer system for quantitative analysis of T cell activation by single molecule imaging., Gordon Research Conference Single Molecule Approaches To Biology, July 2012.
• Tokunaga M., Ichikawa A., Ito Y., Sakata-Sogawa K.. Quantitative spatiotemporal dynamics of T cell signaling using single molecule imaging., Gordon Research Conference Single Molecule Approaches To Biology, July 2012.
• Sakata-Sogawa K., Takimoto J., Tanaka T., Kaisho T., Tokunaga M.. Dynamics of transcription factor proteins in nucleus by single molecule analysis., Gordon Research Conference Single Molecule Approaches To Biology, July 2012.
• Sakata-Sogawa K, Okada A, Ito Y, Tokunaga M. NF-kB activation mechanism regulated by IkBa., 17th international Bophysics Congress, Oct. 2011.
• Fukagawa A., Hiroshima M., Tokunaga M. Stochastic and dynamic behavior of quasi-static mechanical unzipping of single-base pair of DNA on 2D maps, 17th international Bophysics Congress, Oct. 2011.
• Takimoto J., Tanaka T., Kaisho T., Tokunaga M., Sakata-Sogawa K.. Dynamics of spatial-temporal regulation of NF-kB inactivation., 17th international Bophysics Congress, Oct. 2011.
• Ito Y., Sakata-Sogawa K., Tokunaga M.. Quantitation of molecular dynamics and interactions in T cell activation by single-molecule microscopy with a lipid bilayer system., 17th international Bophysics Congress, Oct. 2011.
• Tokunaga M., Sakata-Sogawa K.. Dynamics of proteins in the nucleus by single molecule analysis, International Symposium on the Physicochemical Field for Genetic Activities, Jan. 2011.
• Sakata-Sogawa, K., Tokunaga M.. Detection de molecules uniques sur cellule vivante: presentation d'une nouvelle technique de microscopie a fluorescence, 27eme Rencontre Scientifique Francophone de Tokyo, Aug. 2010.
• Sakata-Sogawa K., Tokunaga M.. Dynamics of transcription factor proteins in nucleus by single molecule analysis, Gordon Research Conference Single Molecule Approaches To Biology, July 2010.
• makio tokunaga. Single molecule imaging in living cells and stochastic feature of molecular interactions, Universität Heidelberg – Tokyo Institute of Technology JOINT WORKSHOP: Life Science and Biological Technology “Life Science for Better Life”, July 2010.
• Fukagawa A., Hiroshima M., Tokunaga M. Stochastic and dynamic pathways detected by quasi-static mechanical unzipping of single-base pair of DNA and MD simulations, Gordon Research Conference Single Molecule Approaches To Biology, July 2010.
• makio tokunaga. TIRF principle and applications with a focus on biological samples., DKFZ/EMBL Practical Course, Mar. 2010.
• Sakata-Sogawa K., Tokunaga M.. Single Molecule Microscopy for Immunological Cell Signaling, Sweden-Japan Joint Colloquium “Current Approaches & Future Perspectives on the Human Genome, Transcriptome & Proteome”, Jan. 2010.
• makio tokunaga. Single Molecule Imaging in Living Cells, 4th Global COE International Symposium Program, May 2009.
• Sakata-Sogawa K., Tokunaga M. Single molecule imaging and quantitative analysis in living cells., EMBO Workshop “Visualizing Immune System Complexity”, Jan. 2009.
• Tokunaga M., Sakata-Sogawa K.. Highly inclined thin illumination enables clear single-molecule imaging in linving cells., 39th NIPS International Symposium & 7th OIB Symposium “Frontiers of Biological Imaging: Synergy of the Advanced Techniques”, Nov. 2008.
• Tokunaga M., Fukagawa A., Sakata-Sogawa K.. Single molecule imaging by HILO microscopy in linving cells and stochastic emergence of multiple intermediates detected by single-molecule protein unfolding., Department of Anatomy & Structural Biology Seminar, Aug. 2008.
• Sakata-Sogawa K., Tokunaga M.. Single molecule imaging and quantitative analysis of transcription factors in living cell by HILO microscopy., Gordon Research Conference Single Molecule Approaches To Biology, Aug. 2008.
• Fukagawa A., Hiroshima M., Sakane I., Kuwajima K., Tokunaga M.. Stochastic emergence of multiple intermediates detected by single-molecule protein unfolding., Gordon Research Conference Single Molecule Approaches To Biology, Aug. 2008.

国内会議発表 (査読有り)

• Yuma Ito, Takahiro Maeda, Kumiko Sakata-Sogawa, Masaaki Shiina, Makio Tokunaga. Dimerization dependent single-molecule dynamics of MafG transcription factor in living cell, The 56th Annual Meeting of the Biophysical Society of Japan, Sept. 2018.
• Takahiro Maeda, Yuma Ito, Shin-Ya Isobe, Chikashi Obuse, Makio Tokunaga. Dynamics of Heterochromatin protein 1α in living cells using single-molecule imaging., The 56th Annual Meeting of the Biophysical Society of Japan, Sept. 2018.
• Shuntaro Sato, Yuma Ito, Yuko Sato, Hiroshi Kimura, Makio Tokunaga. Single-molecule imaging of post-translational modification using genetically encoded antibody probe., The 56th Annual Meeting of the Biophysical Society of Japan, Sept. 2018.
• Wei Ming Lim, Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. CLIP-170 is essential for MTOC repositioning during T cell activation by recruiting proteins to the plus-end tracking on the cell surface, The 56th Annual Meeting of the Biophysical Society of Japan, Sept. 2018.
• Daiki Matsumoto, Yuma Ito, Noriko Saitoh, Kumiko Sakata-Sogawa, Makio tokunaga. Single-Molecule dynamics of nucleolar proteins in different compartments of nucleous, The 55th Annual Meeting of the Biophysical Society of Japan, Sept. 2017.
• Yuma Ito, Kumiko Sakata-Sogawa, Makio tokunaga. An analysis method for quantification of spatiotemporal dynamics and kinetics using single molecule tracking, The 55th Annual Meeting of the Biophysical Society of Japan, Sept. 2017.
• Wei Ming Lim, Yuma Ito, Kumiko Sakata-Sogawa, Makio tokunaga. Quantitative imaging analysis of microtubule-organizing center repositioning meditated by CLIP-170 phosphorylation during T cell activation, The 55th Annual Meeting of the Biophysical Society of Japan, Sept. 2017.
• Shinnosuke Kunimi, Yuma Ito, Hidehisa Takahashi, Kumiko Sakata-Sogawa, Makio tokunaga. Molecular dynamics analysis of Mediator subunit MED26 controlling transportation elongation by fluorescence imaging in the nucleus, The 55th Annual Meeting of the Biophysical Society of Japan, Sept. 2017.
• Takahiro Maeda, Yuma Ito, Shunei Doi, Masaaki Shiina, Kumiko Sakata-Sogawa, Makio Tokunaga. Dynamics changes of transcriptional factor Nrf2 in living cells upon exposure to oxidative stress using single-molecule imaging, The 55th Annual Meeting of the Biophysical Society of Japan, Sept. 2017.
• Yuma Ito, Masahiko Harata, Kumiko Sakata-Sogawa, Makio Tokunaga. ATP dependent dynamics of INO80 chromatin remodeling complex revealed by quantitative fluorescence imaging, The 55th Annual Meeting of the Biophysical Society of Japan, Sept. 2017.
• Noriko Saitoh, Haruka Matsumori, Tokuko Haraguchi, Yuma Ito, Makio Tokunaga, Kumiko Sogawa, Mitsuyoshi Nakao. Formation and maintenance of membrane-less nuclear organelle, the nucleolus, The 40th Annual Meeting of the Japan Neuroscience Society,, July 2017.
• 横山 吟司, 山本 浩志, 山崎 祥他, 十川久美子, 徳永万喜洋, 原田昌彦. 細胞分化における核内アクチンの機能解析, 日本生化学会東北支部会, May 2017.
• 伊藤由馬, 原田昌彦, 木村宏, 十川久美子, 徳永万喜洋. １分子イメージングとFRAPによるINO80クロマチン再構成複合体の核内動態解析, 第8回「光塾」, Dec. 2016.
• Shota Ichikawa, Yuma Ito, Takashi Tanaka, Makio Tokunaga, Kumiko Sakata- Sogawa. Live cell imaging and quantitative analysis of anti-inflammatory protein PDLIM2 activation upon LPS stimulation, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• Daiki Matsumoto, Yuma Ito, Noriko Saitoh, Kumiko Sakata-Sogawa, Makio Tokunaga. Single molecule imaging and quantitative analysis of Nucleolar-localized protein dynamics, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa, Tokunaga Makio. Single-molecule imaging of the INO80 chromatin remodeling complex in the living cell nucleus, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• Changyong Shin, Yuma Ito, Makio Tokunaga, Takashi Tanaka, Kumiko Sakata-Sogawa. PDLIM2-interacting protein MKRN2 functions as a novel E3 ligase for p65 subunit of NF-κB, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• Wei Ming Lim, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa. CLIP-170 phosphorylation mediates repositioning of microtubule-organizing center during T cell activation, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• Shinnnosuke Kunimi, Yuma Ito, Yuki Yamaguchi, Kumiko Sakata-Sogawa, Makio Tokunaga. Quantitative image analysis of dynamics of promoter-proximal pausing related proteins, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• Hengyu Shi, Yuma Ito, Wei Ming Lim, Kumiko Sakata-Sogawa, Makio Tokunaga. Super-resolution analysis of microtubule dynamics on T cell activation, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• Tsubasa Isogaki, Yuma Ito, Shota Ichikawa, Hiroshi Kimura, Masahiko Harata, Kumiko Sakata-Sogawa, Makio Tokunaga. Fluorescence recovery after photobleaching(FRAP) analysis of INO80 chromatin remodeling complex, The 54th Annual Meeting of the Biophysical Society of Japan, Nov. 2016.
• 横山吟司, 山本浩志, 山崎祥他, 十川久美子, 徳永万喜洋, 原田昌彦. 細胞分化における核内アクチンの機能解析, 日本農芸化学会2017年度大会, Mar. 2016.
• 山本浩志, 山崎祥他, 十川 久美子, 徳永 万喜洋, 原田昌彦. 細胞分化における核内アクチンの機能解析, 第33回染色体ワークショップ・第14回核ダイナミクス研究会, Jan. 2016.
• 山崎 祥他, 山本 浩二, 十川 久美子, 徳永 万喜洋, 原田昌彦. 細胞核内アクチンフィラメントのゲノム機能への関与, 第33回染色体ワークショップ・第14回核ダイナミクス研究会, Jan. 2016.
• Yuma Ito, Hiroshi Kimura, Masahiko Harada, Kumiko Sakata-Sogawa, Makio Tokunaga. Dynamics of actin-related protein 4 in living cell nucleus for dynamic chromatin regulation, 第53回日本生物物理学会年会, Sept. 2015.
• Daichi Ikeda, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa. Quantitative analysis of dynamics of negative elongation factor NELF and DSIF by single molecule imaging, 第53回日本生物物理学会年会, Sept. 2015.
• Akihiro Fukagwa, Michio Hiroshima, Makio Tokunaga. Entropic effects of hydrogen bonds to the double-stranded DNA structure revealed by single-molecule mechanical unzipping, 第53回日本生物物理学会年会, Sept. 2015.
• Changyong Shin, Yuma Ito, Kumiko Sakata-Sogawa, Takashi Tanaka, Makio Tokunaga. Identification of PDLIM2 interacting protein using yeast two-hybrid system and quantitative imaging analysis, 第53回日本生物物理学会年会, Sept. 2015.
• Shota Ichikawa, Yuma Ito, Takashi Tanaka, Makio Tokunaga, Kumiko Sakata-Sogawa. Quantitative imaging analysis of anti-inflammatory protein PDLIM2 activation upon LPS stimulation, 第53回日本生物物理学会年会, Sept. 2015.
• Wei Ming Lim, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa. CLIP-170 phosphorylation mediates repositioning of microtubule-organizing center during T cell activation, 第53回日本生物物理学会年会, Sept. 2015.
• Yuma Ito, Tsubasa Isogaki, Hiroshi Kimura, Masahiko Harada, Kumiko Sakata-Sogawa, Makio Tokunaga. Intranuclear dynamics of INO80 chromatin remodeling complex by fluorescent recovery after photobleaching, 第53回日本生物物理学会年会, Sept. 2015.
• 徳永 万喜洋. 生体分子機能の１分子計測とイメージング定量解析, 第12回原子･分子･光科学(AMO)討論会“光を用いた生体内の1分子計測”, June 2015.
• Toriyama Satoshi, Yuma Ito, Takashi Tanaka, Makio Tokunaga, Kumiko Sakata-Sogawa. The elucidation of the molecular mechanism of PDLIM2 activation, The 52th Annual Meeting of the Biophysical Society of Japan, Sept. 2014.
• Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. T cell receptor on the surface of living cells changes in the dynamics inside microclusters revealed by single-molecule imaging analysis, The 52th Annual Meeting of the Biophysical Society of Japan, Sept. 2014.
• Akihiro Fukagawa, Kumiko Sakata-Sogawa, Makio Tokunaga. Formation of microclusters of receptor molecules improves signal/noise ratio in cellular signal transduction, The 52th Annual Meeting of the Biophysical Society of Japan, Sept. 2014.
• Morio Ohki, Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. A series of GECO mutants suitable for calcium imaging in a wide range of calcium concentration, The 52th Annual Meeting of the Biophysical Society of Japan, Sept. 2014.
• Daichi Ikeda, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa. Single molecule imaging and quantitative analysis of dynamics of negative elongation factor NELF, The 52th Annual Meeting of the Biophysical Society of Japan, Sept. 2014.
• 山崎 祥他, 十川 久美子, 徳永 万喜洋, 原田 昌彦. 核内アクチンフィラメントの転写制御への関与とその分子機構の解析, 第32回染色体ワークショップ・第13回核ダイナミクス研究会, 2014.
• Naomichi Inaba, Yuma Ito, Harata Masahiko, Hiroshi Kimura, Makio Tokunaga, Kumiko Sakata-Sogawa. Quantitative analysis of molecular dynamics of Arp4beta upon transcriptional activation by single-molecule fluorescence imaging and FRAP, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• Hirofumi Oyama, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa. FRET-based analysis of interactions between elongin B and elongin C, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. Single molecule analysis of signaling membrane proteins in T cell microcluster by multicolor live cell imaging, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• Toriyama Satoshi, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa. The elucidation of the mechanism of PDLIM2 localization regulation, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• Morio Ohki, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa. Quantification of calcium concentration in cells by imaging analysis using GEM-GECO, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• Wei Ming Lim, Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. Microtubules Organizing Center (MTOC) Dynamics and Migration Upon T Cell Activation, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• Akio Chiba, Akihiro Fukagawa, Kumiko Sakata-Sogawa, Makio Tokunaga. Responses of a stochastic signaling cascade to input signals with extrinsic noise, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• Akihiro Fukagawa, Masashi Kajita, Kumiko Sakata-Sogawa, Makio Tokunaga. Why do cells use signaling cascades with a variety of the number of steps?, The 51th Annual Meeting of the Biophysical Society of Japan, Oct. 2013.
• 徳永万喜洋, 深川暁宏, 十川久美子. １分子研究が明かす動的でエントロピー的な“場”, 遺伝情報場シンポジウム2013, Jan. 2013.
• Nobuyuki Shiina, Makio Tokunaga. Dendritic mRNA transport and local translation are responsible for the formation of neuronal networks, 日本神経科学界第34回年会, Sept. 2011.
• 徳永万喜洋, 十川久美子. シグナル伝達活性化におけるT細胞受容体分子会合の１分子解析, 第47回日本生物物理学会年会, Oct. 2009.
• 徳永万喜洋. 生細胞における１分子イメージング, 東工大フロンティア大隅研セミナー, July 2009.
• 十川久美子, 徳永万喜洋. 薄層斜光照明法による細胞内1分子イメージング, 第46回日本生物物理学会年会, Dec. 2008.
• 深川暁宏, 廣島通夫, 桑島邦博, 徳永万喜洋. スタフィロコッカルヌクレアーゼの分子内構造へのカルシウムイオン効果の１分子力学測定, 第46回日本生物物理学会年会, Dec. 2008.
• Shiina, N., Tokunaga, M.. RNA granule protein RNG105 deficiency impairs the dendritic localization of Na+/K+ ATPase subunit isoforms and the formation of neuronal networks and synapses, Meeting of the Japan Society for Cell Biology, June 2008.
• 深川暁宏, 廣島通夫, 桑島邦博, 徳永万喜洋. 一分子計測およびＭＤシミュレーションによるタンパク質アンフォールディングの確率的経路と複数の中間状態の検出, 第45回日本生物物理学会年会, Dec. 2007.
• 椎名 伸之, 徳永 万喜洋. 神経RNA granuleタンパク質RNG105ノックアウトによる興奮性・抑制性シナプスバランスの異常, 第45回日本生物物理学会年会, Dec. 2007.
• 十川久美子, 徳永万喜洋. １分子イメージングによる転写因子の核内動態解析, 第45回日本生物物理学会年会, Dec. 2007.
• 新倉和美, 十川久美子, 木村宏, 徳永万喜洋. 転写因子の免疫刺激による共局在の変化：マルチカラー分子イメージング, 第45回日本生物物理学会年会, Dec. 2007.

国際会議発表 (査読なし・不明)

• Ito Y, Tokunaga M. Single-molecule localization-integrated trajectory analysis for dynamic interaction of chromatin structure and transcription machinery, 67th Biophysical Society Annual Meeting, Feb. 2023.
• Ito Y, Tokunaga M. Simultaneous single molecule imaging of RNA polymerase II dynamics and chromatin nanostructures in living cells, 66th Biophysical Society Annual Meeting (Online), Feb. 2022.

国内会議発表 (査読なし・不明)

• 岡 寿, 伊藤 由馬, 周 翔, 徳永 万喜洋. １分子蛍光顕微鏡像の３次元位置を高精 度に計測できる深層学習を用いた方法のシミュレーション研究, Dec. 2023.
• 廣瀬 仁教, 伊藤 由馬, 徳永 万喜洋. 2C12 筋芽細胞の分化過程におけ る核内1 分子動態の変化, 第61 回日本生物物理学会年会, Nov. 2023.
• 安彦 穂高, 伊藤 由馬, 徳永 万喜洋. 高速拡散1 分子の位置推定精度向 上にむけた軌跡追跡シミュレーション解析, 第61 回日本生物物理学会年会, Nov. 2023.
• 伊藤 由馬, 徳永 万喜洋. 生細胞における転写中のRNA ポリメラーゼII 分子の力学的特性, 第61 回日本生物物理学会年会, Nov. 2023.
• 伊藤 由馬, 佐々木 亮太, 大平 皐介, 周 翔, 徳永 万喜洋. 補 償光学系による位相変調と機械学習を用いて1 分子輝点3 次元座標を光軸 方向に広範囲に高精度計測する方法のシミュレーション研究, 第61 回日本 生物物理学会年会, Nov. 2023.
• 廣瀬 仁教, 伊藤 由馬, 徳永 万喜洋. 細胞分化に伴うクロマチン構造における状態特異的なヒストン動態の1分子イメージング, 第60回日本生物物理学会, Sept. 2022.
• Yuko Sato, Yuma Ito, Satoshi Uchino, Makio Tokunaga, Hiroshi Kimura. Chromatin mobility of X-linked loci and its epigenetic regulation, 第60回日本生物物理学会年会, Sept. 2022.
• 伊藤 由馬, 徳永 万喜洋. 1分子動態と局在による機能的クロマチン-RNA polymerase Ⅱ相互作用の統合解析, 第60回日本生物物理学会年会, Sept. 2022.
• 周 翔, 伊藤 由馬, 徳永 万喜洋. 補償光学系と機械学習を用いて1分子輝点の3次元座標を精度良く計測する方法のシミュレー ション研究, 第60回日本生物物理学会年会, Sept. 2022.
• 秋田 嶺, 伊藤 由馬, 徳永 万喜洋. 一分子イメージングを用いた生細胞内RNAポリメラーゼIIの様々な転写サイクル段階における ダイナミクス解析, 第60回日本生物物理学会年会, Sept. 2022.
• 内野 哲志, 伊藤 由馬, 佐藤 優子, 半田 哲也, 大川 恭行, 徳永 万喜洋, 木村 宏. リン酸化型RNAポリメラーゼII可視化プローブによる転写部位の生細胞観察, 第39回染色体ワークショップ・第20回核ダイナミクス研究会, オンライン, Dec. 2021.
• 内野 哲志, 伊藤 由馬, Jessica Dai, 佐藤 優子, 半田 哲也, 大川 恭行, 徳永 万喜洋, 木村 宏. 転写伸長型RNAポリメラーゼII可視化プローブによる生細胞内における 転写伸長部位の観察, 第44回日本分子生物学会年会, Dec. 2021.
• Noriko Saitoh, Haruka Matsumori, Kenji Watanabe, Hiroaki Tachiwana, Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga, Akinori Awatsu, Mitsuyoshi Nakao. RPL5 maintains spatial organization of the ribosomal DNA arrays through regulation of biophysical properties of the nucleolus, 第44回日本分子生物学会年会, Dec. 2021.
• Masanori Nakano, Yuma Ito, makio tokunaga. Structural changes in heterochromatin involved in cell cycle using single-molecule and super-resolution imaging, 第59回日本生物物理学会年会, Nov. 2021.
• 佐藤優子, 内野哲志, 伊藤由馬, 前原一満, 大川恭行, 徳永万喜洋, 木村宏. 生細胞プローブを用いた不活性化X染色体動態と転写制御の解析, 第94回 日本生化学会大会, Nov. 2021.
• 伊藤 由馬, 徳永 万喜洋. １分子超解像イメージングを用いたRNA ポリメラーゼII とクロマチンのナノスケール相互作用解析, 第59回日本生物物理学会年会, オンライン, Nov. 2021.
• Yuma Ito, Sirisukhodom Spanut, makio tokunaga. Single-molecule imaging analysis of RNA-dependent dynamics of phase-separated nucleolar proteins in living cells, 第59回日本生物物理学会年会, Nov. 2021.
• Xiang Zhou, Yuma Ito, makio tokunaga. A simulation study to evaluate improvementof three-dimensional localization precision of single molecule images using adaptive optics., 第59回日本生物物理学会年会, Nov. 2021.
• Masanori Hirose, Yuma Ito, makio tokunaga. Single-molecule analysis of state-specific histone mobility in chromatin subcompartments with different epigenetic modifications, 第59回日本生物物理学会年会, Nov. 2021.
• 徳永 万喜洋. 授業中のこまめな小問解きと、課題提出へのフィードバック ─ 物理化学第二 ─, 教育革新シンポジウム2020「東工大オンライン授業のグッドプクティス1」, Oct. 2020.
• 徳永 万喜洋. 多色１分子イメージングによる免疫細胞活性化における中心体移動とマイクロ クラスター形成の機構, HiHA Web セミナー, Oct. 2020.
• Yuma Ito, MakioTokunaga. Nano-scale localization analysis of histone variants in living cells using single-molecule super-resolution imaging, The 58th Annual Meeting of the BSJ, Sept. 2020.
• Yuma Ito, MakioTokunaga. Quantification of dynamics and kinetics using single-molecule and super-resolution imaging in living cells, The 58th Annual Meeting of the BSJ, Sept. 2020.
• Masanori Nakano, Yuma Ito, Takahiro Maeda, Chikashi Obuse, MakioTokunaga. Dynamics of Heterochromatin protein 1α inside and outside chromocenter domain in living cells using single-molecule imaging, The 58th Annual Meeting of the BSJ, Sept. 2020.
• Supanut Sirisukhodom, Yuma Ito, MakioTokunaga. Multicolor single-molecule imaging analysis of the nucleolar proteins, The 58th Annual Meeting of the BSJ, Sept. 2020.
• Xiang Zhou, Yuma Ito, MakioTokunaga. Light field simulation of single-molecule imaging for aberration correction using adaptive optics, The 58th Annual Meeting of the BSJ, Sept. 2020.
• Yuma Ito, MakioTokunaga. A single-molecule localization approach to quantify the interaction between transcriptional machinery and chromatin structure, The 57th Annual Meeting of the BSJ, Sept. 2019.
• Yuma Ito, Shinnosuke Kunimi, Hidehisa Takahashi, Makio Tokunaga. Molecular localization and dynamics of Mediator regulating transcription elongation using single-molecule and super-resolution microscopy, The 57th Annual Meeting of the BSJ, Sept. 2019.
• Takahiro Maeda, Yuma Ito, Shin-Ya lsobe, Chikashi Obuse, Makio Tokunaga. Dynamics and localization of Heterochromatin protein 1a invoIved in phase separation using single-molecule and super-resolution imaging., The 57th Annual Meeting of the BSJ, Sept. 2019.
• Yuma Ito, makio tokunaga. Single-molecule super-resolution imaging of chromatin proteins for quantification of nanoscale dynamics and localization, Symposium “Regulation of transcription in the context of chromatin and nuclear structures, Joint Annual Meeting of 71th JSCB & 19th PSSJ, June 2019.
• Yuma Ito, Shinnosuke Kunimi, Hidehisa Takahashi, Makio Tokunaga. Molecular localization and dynamics of Mediator regulating transcription elongation using single-molecule and super-resolution microscopy, The 57th Annual Meeting of the BSJ, 2019.
• Supanut Sirisukhodom, Daiki Matsumoto, Yuma lto, Noriko Saitoh, Kumiko Sakata-Sogawa, Makio Tokunaga. Single-molecule dynamics and localization of nucleolar proteins in phase-separated compartments of nucleolus, 第57回日本生物物理学会年会, 2019.
• 伊藤由馬, 徳永万喜洋. 生細胞1分子イメージングによるクロマチン動態の定量解析, 科研費新学術領域「クロマチン潜在能」第１回班会議, Sept. 2018.
• 伊藤 由馬, 十川 久美子, 徳永 万喜洋. 蛍光１分子イメージングにおける動態解析法の開発と核内タンパク質挙動の定量解析, シンポジウム「クロマチンの動態と調節を新技術で捉える試み」, 第91回日本生化学会大会, Sept. 2018.
• Ito Y, Takimoto J, Tanaka T, Kaisho T, Sakata-Sogawa K, Tokunaga M.. Molecular imaging analysis of regulatory mechanism of inflammatory response., 58th Annual Meeting of Biophysical Society, Dec. 2014.
• Wei Ming Lim, Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. Microtubules Instability and Dynamics Mediated by CLIP-170 in T Cells, The 37th Annual Meeting of the Molecular Biology Society of Japan, Nov. 2014.
• Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. Live cell single-molecule imaging of T cell receptor and microcluster with planar lipid bilayers,, The 37th Annual Meeting of the Molecular Biology Society of Japan, Nov. 2014.
• Shota Yamazaki, Kumiko Sakata-Sogawa, Makio Tokunaga, Masahiko Harata. Functional regulation of the dynamics of actin in the nucleus, The 87th Annual Meeting of the Japanese biochemical Society, Oct. 2014.
• Yu Matsushima, Osamu Toda, Yuma Ito, Kumiko Sakata-Sogawa, Thanai Paxton, Akiyoshi Boku, Satoshi Ohno, Takayuki Yonezawa, Takashi Yokogawa, Kazuya Nishikawa, Ung-il Chung, Makio Tokunaga, Nobuhiro Hayashi. Action mechanism of neuronal membrane lipid raft, The 36th Annual Meeting of the Molecular Biology Society of Japan, Dec. 2013.
• 山崎祥他, 十川久美子, 徳永万喜洋, 原田昌彦. エピジェネティック制御における核内アクチン骨格の関与の解析, 第30回染色体ワークショップ・第11回核ダイナミクス研究会, Dec. 2012.
• 戸田 収, 細谷 悟史, 遠藤 毅, 根岸 瑠美, 福島 慶子, 伊藤 由馬, 十川 久美子, PAXTON Thanai, 喜井 勲, 朴 明宣, 大野 敏, 竹内 真粧美, 横川 隆志, 西川 一八, 山下 克子, 徳永 万喜洋, 細谷 孝充, 林 宣宏. 神経細胞における生体膜ラフトの動作メカニズムの解明, 第35回日本分子生物学会年会, Dec. 2012.
• Yuma Ito, Hirofumi Oyama, Kumiko Sakata-Sogawa, Makio Tokunaga. Single molecule analysis of T cell activation with stimulatory lipid bilayers by live cell imaging, The 50th Annual Meeting of the Biophysical Society of Japan, Sept. 2012.
• Masahiro Shimozawa, Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. Spatial-temporal dynamics of calcium signaling and organelles in T cell activation, The 50th Annual Meeting of the Biophysical Society of Japan, Sept. 2012.
• Akihiro Fukagwa, Michio Hiroshima, Makio Tokunaga. GC and AT pairs show different entropic stabilization of DNA structures found in single-molecule mechanical unzipping, The 50th Annual Meeting of the Biophysical Society of Japan, Sept. 2012.
• Hirofumi Oyama, Yuma Ito, Satoshi Ikeda, Kumiko Sakata-Sogawa, Makio Tokunaga. Dynamics of intracellular Ca2+ distribution measured by genetically encoded Ca2+ indicators, The 50th Annual Meeting of the Biophysical Society of Japan, Sept. 2012.
• Naomichi Inaba, Yuma Ito, Masahiko Harata, Makio Tokunaga, Kumiko Sakata-Sogawa. Imaging anaysis of Arp4β mutants in ATP-binding site, The 50th Annual Meeting of the Biophysical Society of Japan, Sept. 2012.
• Katsuo Ichinomiya, Masahiko Harata, Kumiko Sakata-Sogawa, Makio Tokunaga. Quantitative analysis of changes in molecular dynamics of Arp4 upon transcriptional activation using single-molecule fluorescence imaging, The 50th Annual Meeting of the Biophysical Society of Japan, Sept. 2012.
• Akihiro Fukagawa, Michio Hiroshima, Makio Tokunaga. Entropic stabilization of DNA structures by hydrogen bonds found in mechanical unzipping, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Arata Ichikawa, Kumiko Sakata-Sogawa, Makio Tokunaga. Quantitative spatio-temporal analysis of dynamics of T cell signaling molecules on activation, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Keitaro Kato, Junichi Tashiro, Sigenori Miyawaki, Kouhei Ebe, Makio Tokunaga. Simplified coarse-grained model of cellular membranes to simulate dynamic features of cells, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Ryuta Okada, Katsuo Ichinomiya, Yasushi Fujimoto, Katsuyuki Abe, Yoshihiro Ue, Kumiko Sakata-Sogawa, Makio Tokunaga. Multifocal plane microscopy for three-dimensional molecular imaging and quantificationin living cells, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Masahiro Shimozawa, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa. Spatial-temporal dynamics of calcium signaling in T cell activation, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Jun Takimoto, Takashi Tanaka, Tsuneyasu Kaisho, Makio Tokunaga, Kumiko Sakata-Sogawa. Single molecule imaging analysis of NF-κB inactivation by PDLIM2, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Ichinomiya Katsuo, Timothy J Stasevich, Hiroshi Kimura, Kumiko Sakata-Sogawa, Makio Tokunaga. Spatio-temporal quantitative analysis of molecular dynamics and interactions in cells using multicolor single-molecules imaging, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Masashi Kajita, Kumiko Sakata-Sogawa, Makio Tokunaga. Role of a stochastic cascade reaction in the signal transduction system from the viewpoint of information processing, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. Quantitation of molecular dynamics and interactions in T cell activation by single-molecule microscopy with a lipid bilayer system, The 49th Annual Meeting of the Biophysical Society of Japan, Sept. 2011.
• Masashi Kajita, Makio Tokunaga. Signal amplification and extinction caused by propagation of fluctuation in a signal transduction pathway, 第48回日本生物物理学会年会, Sept. 2010.
• Keitaro Kato, Junichi Tashiro, Shigenori Miyawaki, Kouhei Ebe, Makio Tokunaga. Simplified coarse-grained model of cellular membranes to simulate dynamic features of cells, 第48回日本生物物理学会年会, Sept. 2010.
• Arata Ichikawa, Kumiko Sakata-Sogawa, Makio Tokunaga. Single molecule analysis of dynamics of T cell signaling molecules on activation, 第48回日本生物物理学会年会, Sept. 2010.
• Jun Takimoto, Takashi Tanaka, Tsuneyasu Kaisho, Makio Tokunaga, Kumiko Sakata-Sogawa. Clarification of Spatial-temporal regulation of NF-κB inactivation by single molecule fluorescence microscopy, 第48回日本生物物理学会年会, Sept. 2010.
• Yuma Ito, Kumiko Sakata-Sogawa, Makio Tokunaga. Single molecule imaging and quantitative analysis of activation of T cell signaling with stimulatory lipid bilayers, The 48th Annual Meeting of the Biophysical Society of Japan, Sept. 2010.
• Akira Okada, Makio Tokunaga, Kumiko Sakata-Sogawa. single molecule imaging analysis of NF-κB activation mechanism regulated by IκBα, 第48回日本生物物理学会年会, Sept. 2010.
• Akihiro Fukagawa, Michio Hiroshima, Makio Tokunaga. Stochastic and dynamic behavior of quasi-static mechanical unzipping of single-base pair of DNA on 2D maps, 第48回日本生物物理学会年会, Sept. 2010.
• Shiina, N., Tokunaga, M.. RNG105 and RNG140: mRNA transport granule proteins responsible for the maintenance and development of neuronal dendrites, 第62回日本細胞生物学会大会, May 2010.
• Akihiro Fukagawa, Michio Hiroshima, Makio Tokunaga. Stochastic and dynamic pathways detected by quasi-static mechanical unzipping of single-base pair of DNA and MD simulations, 第47回日本生物物理学会年会, Oct. 2009.
• 十川久美子, 徳永万喜洋. 免疫細胞活性化初期過程の1分子イメージング解析, 科研費特定領域研究「マルチスケール操作によるシステム細胞工学（バイオ操作）」公開シンポ「分野横断的手法を活用した新時代の生命科学研究」, Aug. 2009.
• 深川暁宏, 廣島通夫, 桑島邦博, 徳永万喜洋. スタフィロコッカルヌクレアーゼの分子内構造へのカルシウムイオン効果の１分子力学測定, 科研費特定領域研究「マルチスケール操作によるシステム細胞工学（バイオ操作）」公開シンポ「分野横断的手法を活用した新時代の生命科学研究」, Aug. 2009.
• Shiina, N., Tokunaga, M.. RNA granule protein RNG140 is a paralog of RNG105 and localized to distinct RNA granules in the brain of adult vertebrates, 第61回日本細胞生物学会大会, June 2009.

その他の論文・著書など

• 十川久美子, 徳永万喜洋. 免疫細胞表面の1分子イメージング計測, 現代化学, Vol. 488, No. 11, p. 42-43, Oct. 2011.
• 徳永万喜洋, 十川久美子. 薄層斜光照明法による細胞内での蛍光１分子観察, 生物物理, 日本生物物理学会, Vol. 49, No. 6, pp. 318-321, Dec. 2009.
• 徳永万喜洋. １分子イメージング：できないと言われたことにチャレンジ, 蛋白質 核酸 酵素, 共立出版株式会社, Vol. 54, No. 6, pp. 772-778, May 2009.
• 十川 久美子, 徳永 万喜洋. 免疫細胞シグナルの1分子イメージングと分子動態, 生化学, 81, 3, pp. 218-222, Mar. 2009.
• 椎名伸之, 徳永万喜洋. 神経シナプス可塑性の分子イメージング, Clinical Neuroscience, 中外医学社, Vol. 26, No. 10, pp. 1062-1063, Oct. 2008.
• 徳永万喜洋, 十川久美子. 薄層斜光照明法でみえてくる新たな生命現象, 実験医学, Vol. 26, No. 17, pp. 163-168, Oct. 2008.
• 徳永万喜洋, 十川久美子. 従来の８倍の高画質で生体分子１個を見る顕微鏡法を開発, Medical Bio, Vol. 5, No. 2, pp. 16-17, Mar. 2008.
• 十川久美子, 徳永万喜洋. 細胞内蛍光１分子イメージング, 遺伝子医学MOOK 9, pp. 192-196, Feb. 2008.
• 徳永万喜洋, 十川久美子. 細胞１分子イメージングと定量解析～シグナル伝達の可視化, バイオテクノロジージャーナル, Vol. 7, No. 3, pp. 659-663, Nov. 2007.
• 十川久美子, 徳永万喜洋. 免疫分子動態の可視化システム, 日本臨床, Vol. 65, No. 2, pp. 242-246, Feb. 2007.
• 椎名伸之, 徳永万喜洋. 神経シナプス可塑性における局所的翻訳の制御機構, 蛋白質 核酸 酵素, Vol. 51, No. 8, pp. 943-949, Apr. 2006.
• 徳永 万喜洋. 生きた細胞内でうごめく「分子の振舞い」をダイナミックな映像で可視化 ”次世代テクノロジーリーダー100人”, ダイヤモンド（ループ）, ダイヤモンド社, No. 4, p. 38, 2004.
• 徳永 万喜洋. 見えなかった物を観る－無理と言われたテーマに挑戦－, 科学技術ジャーナル, 科学技術広報財団, Vol. 11, No. 10, p. 52-53, 2002.
• 喜多村和郎, 岩根敦子, 徳永万喜洋. ミオシン頭部１分子はＡＴＰ分解１回で複数ステップ動く－１分子捕捉・操作によるルースカップリングの直接証拠－, 生物物理, 生物物理学会, Vol. 40, No. 2, pp. 89-93, 2000.
• 徳永万喜洋, 喜多村和郎. ミオシン１分子は１個ＡＴＰ分解の間に複数ステップで動く, 蛋白質核酸酵素, 共立出版, Vol. 44, No. 11, pp. 1584-1589, Sept. 1999.
• 廣島通夫, 徳永万喜洋. 分子間相互作用のイメージング－分子間力顕微鏡と１分子技術－, 電子顕微鏡, Vol. 34, No. 2, pp. 151-153, Sept. 1999.
• 徳永万喜洋. ミオシン１分子の反応と動きを追う, 細胞工学, 学研メディカル秀潤社, Vol. 18, No. 11, pp. 1641-1647, 1999.
• 徳永万喜洋. 生体分子機能の一分子直視と計測, 現代化学, No. 328, page 26-30, 1998.
• 石島秋彦, 小嶋寛明, 徳永万喜洋. 生体分子機能の１分子イメージング, 蛋白質・核酸・酵素, 共立出版, Vol. 43, No. 10, pp. 1365-1371, 1998.
• 廣島通夫, 徳永万喜洋. 分子間力顕微鏡と１分子技術, 応用物理学会 有機分子・バイオエレクトロニクス分科会会誌, Vol. 9, No. 4, pp. 156-162, 1998.
• 徳永万喜洋. 分子間相互作用のイメージング－アクチン・ミオシン系を中心として－, 蛋白質・核酸・酵素, 共立出版, Vol. 42, No. 7, pp. 1209-1214, 1997.
• 徳永万喜洋. 筋収縮の分子モーター － 単一アクチンフィラメントの力を測る, 現代の細胞生物学, 講談社, pp. 14-19, Mar. 1996.
• 徳永万喜洋, 杉本泰伸, 若林克三. Ｘ線溶液散乱でとらえたエネルギー変換中のミオシン頭部の構造変化, 生物物理, 日本生物物理学会, Vol. 34, No. 3, pp. 272-280, 1994.
• 徳永万喜洋. 筋収縮研究の流れとナノバイオロジー, 蛋白質・核酸・酵素, 共立出版, Vol. 39, No. 3, pp. 272-280, 1994.
• 徳永万喜洋. 3次元電子顕微鏡画像処理, 電子顕微鏡, Vol. 26, No. 2, pp. 182-183, 1991.
• 徳永万喜洋. アビジン分子を直接利用する方法, 生体の科学, Vol. 40, No. 4, pp. 308, 1989.
• 須藤和夫, 徳永万喜洋, 若林健之. クロスブリッジの三次元構造, 蛋白質核酸酵素, Vol. 34, No. 13, pp. 1769-1775, 1989.
• 徳永万喜洋, 若林健之, 須藤和夫. ミオシンATP結合部位の電子顕微鏡による三次元位置の決定, 生物物理, Vol. 29, No. 2, pp. 51-53, 1989.
• 秋葉俊彦, 徳永万喜洋, 若林健之. X線回析法と電子顕微鏡法による生体超分子構造体の構造解析－筋肉フィラメントの構造－, 月刊フィジックス, Vol. 7, No. 7, pp. 448-457, 1986.

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