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山本直之 研究業績一覧 (149件)
論文
-
Satoru Kuriu,
Naoyuki Yamamoto,
Tadashi Ishida.
Development of a microfluidic device to observe dynamic flow around the villi generated by deformation of small intestinal tissue,
Lab on a Chip,
Vol. 23,
pp. 2729-2737,
June 2023.
公式リンク
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Changge Guan,
Zheng Lin Tan,
Shucheng Li,
Yi Wang,
Naoyuki Yamamoto,
Chong Zhang,
Songjun Wang,
Junjie Chen,
Xin-Hui Xing.
Transcriptomic Analysis of Andrias davidianus Meat and Experimental Validation for Exploring Its Bioactive Components as Functional Foods,
Food Science and Human Wellness,
Sept. 2022.
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Zheng Lin Tan,
Kazuhiko Miyanaga,
Yoshitaka Kitamoto,
Naoyuki Yamamoto.
Levilactobacillus brevis surface layer protein B promotes liposome targeting to antigen-presenting cells in Peyer’s patches,
International Journal of Pharmaceutics,
Vol. 622,
p. 121896,
June 2022.
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Satoru Kuriu,
Naoyuki Yamamoto,
Tadashi Ishida.
Microfluidic Device Using Mouse Small Intestinal Tissue for the Observation of Fluidic Behavior in the Lumen,
Micromachines,
Vol. 12,
No. 6,
June 2021.
-
Shun Iwatani,
Naoyuki Yamamoto.
Functional food products in Japan: A review,
Food Science and Human Wellness,
Mar. 2019.
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Naoyuki Yamamoto,
Taketo Wakai.
Genome-wide motif predictions of BCARR-box in the amino-acid repressed genes of Lactobacillus helveticus CM4,
BMC Microbiology,
Vol. 17,
224,
Dec. 2017.
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Yanagihara, S.,
Fukuda, S.,
Kanaya, T.,
Nakato, G.,
Hanazato, M.,
Wu, X.,
Yamamoto, N.,
Ohno, H..
Uromodulin-SlpA binding dictates Lactobacillus acidophilus uptake by intestinal epithelial M cells.,
Int. Immunol.,
Vol. 29,
357-463.,
2017.
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Kurosawa, M.T.,
Nakamura, Y.,
Yamamoto, N.,
Yamada, K.,
Iketani, T..
Effects of Val-Pro-Pro and Ile-Pro-Pro on nondipper patients: a preliminary study.,
J Med Food,
Vol. 14,
538-542.,
2017.
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Matsuura, K.,
Goto, T.,
Kawaguchi, K.,
Mizuno, S.,
Yamamoto, N..
Release of antihypertensive peptides, Val-Pro-Pro and Ile-Pro-Pro, in Blue, Dutch and Swiss cheeses.,
Milk Science, 66: 97-106.,
Vol. 66,
97-106.,
2017.
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Yanagihara, S.,
Kato, S.,
Ashida, N.,
,
Yamamoto, N..
Lactobacillus acidophilus CP23 with weak immunomodulatory activity lacks anchoring structure for surface layer protein.,
J Biosci Bioeng.,
Vol. 119,
521-525.,
2015.
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Yanagihara, S.,
Goto, H.,
Hirota, T.,
Fukuda, S.,
Ohno, H.,
Yamamoto, N..
Lactobacillus acidophilus L-92 cells activate expression of immunomodulatory genes in THP-1 cells.,
Bioscience of Microbiota, Food and Health,
Vol. 33,
4,
157-164,
Oct. 2014.
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Wakai, T.,
Yamamoto, N..
A novel branched chain amino acids responsive transcriptional regulator, BCARR, negatively acts on the proteolytic system in Lactobacillus helveticus.,
PLoS One.,
Volume 8,
10,
e75976.,
Oct. 2013.
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Wakai, T.,
Shinoda, T.,
Uchida, N.,
Hattori, M.,
Nakamura, Y.,
Beresford, T.,
Beresford, T.,
Yamamoto, N..
Comparative analysis of proteolytic enzymes need for processing of antihypertensive peptides between Lactobacillus helveticus CM4 and DPC4571.,
J Biosci Bioeng.,
J Biosci Bioeng.,
Vol. 115,
246-252.,
2013.
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Goto, H.,
Sagitani, A.,
Ashida, N.,
Kato, S.,
Hirota, T.,
Shinoda, T.,
Yamamoto, N..
Anti-influenza virus effects of both live and non-live Lactobacillus acidophilus L-92 accompanied by the activation of innate immunity.,
Br J Nutr.,
Vol. 110,
1810-1918.,
2013.
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Nakamura, T.,
Hirota, T.,
Mizushima, K.,
Ohki, K.,
Naito, Y.,
Yamamoto, N.,
Yoshikawa, T..
Milk-derived peptides, Val-Pro-Pro and Ile-Pro-Pro, attenuate atherosclerosis development in apolipoprotein e-deficient mice: a preliminary study.,
J Med Food.,
Vol. J Med Food. 16,
396-403.,
2013.
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Kuwana, R.,
Yamamoto, N..
Increases in GroES and GroEL from Lactobacillus acidophilus L-92 in response to a decrease in medium pH, and changes in cytokine release from splenocytes: Transcriptome and proteome analyses.,
J Biosci Bioeng.,
Vol. 114,
9-16.,
2012.
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Yanagihara, S.,
Hirota, T.,
Yamamoto, N..
Transcriptional response of Lactobacillus acidophilus L-92 after attachment to epithelial Caco-2 cells.,
J Biosci Bioeng.,
Vol. 114,
582-585.,
2012.
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Wakai, T.,
Yamaguchi, N.,
Hatanaka, M.,
Nakamura, Y.,
Yamamoto, N..
Repressive processing of antihypertensive peptides, Val-Pro-Pro and Ile-Pro-Pro, in Lactobacillus helveticus fermented milk by added peptides.,
J Biosci Bioeng.,
Vol. 114,
133-137.,
2012.
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Kawaguchi, K.,
Nakamura, T.,
Kamiie, J.,
Takahashi, T.,
Yamamoto, N..
Accumulation of ACE inhibitory tripeptides, Val-Pro-Pro and Ile-Pro-Pro, in vascular endothelial cells,
Biosci Biotechnol Biochem.,
Vol. 76,
9,
1792-1795.,
2012.
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Yanagihara, S.,
Fukuda, S.,
Ohno, H.,
Yamamoto, N..
Exposure to probiotic Lactobacillus acidophilus L-92 modulates gene expression profiles of epithelial Caco-2 cells.,
2012.
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Hatanaka, M.,
Nakamura, Y.,
Maathuis, A.J.,,
Venema, K.,
Murota, I.,
Yamamoto, N.,
.
Influence of Bacillus subtilis C-3102 on microbiota in a dynamic in vitro model of the gastrointestinal tract simulating human conditions.,
Benef Microbes.,
Vol. 3,
229-236.,
2012.
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Ashida, N.,
Yanagihara, S.,
Shinoda, T.,
Yamamoto、N..
Characterization of adhesive molecule with affinity to Caco-2 cells in Lactobacillus acidophilus by proteome analysis.,
J Biosci Bioeng.,
Vol. 112,
333-337.,
2011.
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Nakamura, T.,
Mizutani, J.,
Ohki, K.,
Yamada, K.,
Takeshi, M.,
Yamamoto, N.,
Takazawa, K..
Casein hydrolysate containing Val-Pro-Pro and Ile-Pro-Pro improves central blood pressure and arterial stiffness in hypertensive subjects: a randomized, double-blind, placebo-controlled trial.,
Atherosclerosis,
Vol. 219,
298-303.,
2011.
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Yamaguchi, N.,
Kawaguchi, K.,
Yamamoto, N..
Study of the Mechanism of Antihypertensive Peptides VPP and IPP in Spontaneously Hypertensive Rats by DNA Microarray Analysis.,
European J Pharmacology,
Vol. 620,
71-77.,
2009.
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Gotou, T.,
Shinoda, T.,
Mizuno, S.,
Yamamoto, N..
Purification and identification of proteolytic enzymes from Aspergillus oryzae capable of the production of the antihypertensive peptide, Ile-Pro-Pro.,
J. Bioscience and Bioengineering.,
Vol. 107,
615-619.,
2009.
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Nakamura, T.,
Mizutani, J.,
Sasaki, K.,
Yamamoto, N.,
Takazawa, K..
Beneficial Potential of Casein Hydrolysate Containing Val-Pro-Pro and Ile-Pro-Pro on Central Blood Pressure and Hemodynamic Index. A Preliminary Study.,
J Med Food.,
Vol. 12,
1221-1226.,
2009.
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Inoue, K.,
Gotou, T.,
Mizuno, S.,
Yamamoto, N..
Release of antihypertensive peptides by adding of casein during miso paste fermentation.,
J. Bioscience and Bioengineering.,
Vol. 108,
111-115.,
2008.
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Matuura, K.,
Mizuno, S.,
Nishimura, S.,
Gotou, T.,
Yamamoto, N..
Quantitative analysis of antihypertensive peptides, Val-Pro-Pro and Ile-Pro-Pro, in casein hydrolyzate with Aspergillus oryzae protease: an LC-MS method.,
Milchwissenschaft,
Vol. 60,
24-27.,
2005.
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Ishida, Y.,
Nakamura, F.,
Kanzato, H.,
Sawada, D.,
Yamamoto, N.,
Kagata, H.,
Oh-ida, M.,
Takeuchi, H.,
Fujiwara, S..
Effect of milk fermented with Lactobacillus acidophilus strain L-92 on symptoms of Japanese cedar pollen allergy: A randomized placebo-controlled trial,
Biosci Biotechnol Biochem.,
Vol. 69,
9,
1652-1660,
2005.
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Mizuno, S.,
Matsuura, K.,
Gotou, T.,
Nishimura, S.,
Kajimoto, O.,
Yabune, M,
Kajimoto, Y.,
Yamamoto, N..
Antihypertensive effect of casein hydrolyzate prepared using an Aspergillus oryzae protease in a placebo-controlled clinical study for subjects with high-normal blood pressure and mild-hypertension.,
British J Nutr.,
Vol. 94,
84-91.,
2005.
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Ueno, K.,
Mizuno, S.,
Yamamoto, N..
Purification and characterization of an endopeptidase that has an important role in the carboxyl terminal processing of antihypertensive peptides in Lactobacillus helveticus CM4.,
Letters in Applied microbiology,
Vol. 39,
4,
313-318,
Aug. 2004.
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Mizuno, S.,
Nishimura, S.,
Matuura, K.,
Gotou, T.,
Yamamoto, N..
Release of sort and proline rich antihypertensive peptides from casein hydrolyzate with an Aspergillus oryzae protease.,
J. Dairy Sci.,
Vol. 87,
183-188.,
2004.
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Yamamoto, N.,
Shinoda, T,,
Mizuno, S..
Cloning and expression of an endopeptidase gene from Lactobacillus helveticus CM4 involved in processing antihypertensive peptides.,
Milchwissenschaft,
Vol. 59,
593-597,
2004.
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Ishida, Y.,
Bandou, I.,
Kanzato,H,
Yamamoto, N..
Decrease in ovalbumin specific IgE of mice serum after oral uptake of lactic acid bacteria,
Biosci Biotechnol Biochem.,
Vol. 67,
5,
951-957.,
2003.
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Shinoda, T.,
Kusuda, D.,
Ishida, Y.,
Kaneko, K.,
Masuda, O.,
Yamamoto, N..
Survival of Lactobacillus helveticus CP53 strain in the human gastrointestinal tract.,
Letters in Applied Microbiology,
Vol. 32,
2,
108-113,
2001.
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Yamamoto, N.,
Shinoda, T.,
Takano, T..
Molecular cloning and sequence analysis of a gene encoding an extracellular proteinase from Lactobacillus helveticus CP790.,
Biosci. Biotechnol. Biochem.,
Vol. 64,
6,
1217-1222,
2000.
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石田 優,
楠田大輔,
池田なぎさ,
金子京子,
高野俊明,
山本直之.
ヒト腸管内で生残性の良いLactobacillus acidophilus L92株の単離とその性質,
乳酸菌学会誌,
Vol. 12,
28-35.,
2000.
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池田なぎさ,
金子京子,
江尻昌弘,
水谷潤,
大島潔,
梶本修身,
高橋丈生,
山本直之.
乳酸菌飲料摂取による便秘傾向を有する健常者の排便状況の改善効果,
健康・栄養食品研究,
Vol. 3,
59-68.,
2000.
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Yamamoto, N.,
Maeno, M.,
Takano, T..
Purification of the antihypertensive peptide from yogurt-like puroduct.,
J. Dairy Sci.,
Vol. 82,
1388-1393.,
1999.
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Yamamoto, N.,
Ono, H.,
Maeno, M.,
Takano, T..
Immunological classification of the extracellular proteinase in Lactobacillus helveticus.,
Biosci. Biotechnol. Biochem.,
Vol. 62,
6,
1228-1230,
1998.
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Ono, H.,
Yamamoto, N.,
Maeno, M.,
Takno, T..
Purification and characterization of a cell-wall associated proteinase from Lactobacillus helveticus CP53.,
Milchwissenschaft,
Vol. 52,
373-377.,
1997.
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Yamamoto, N.,
Takano, T..
Maturation protein need for activation of an extracellular proteinase in Lactobacillus helveticus CP790.,
J. Dairy Sci.,
Vol. 80,
1949-1954.,
1997.
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Yamamoto, N.,
Takano, T..
Isolation and characterization of a small plasmid from Lactobacillus helveticus CP53.,
Biosci. Biotech. Biochem.,
Vol. 60,
12,
2069-2070,
1996.
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Yamamoto, N.,
Masujima, Y.,
Takno, T..
Reduction of membrane-bound ATPase activity in a Lactobacillus helveticus strain with slower growth at low pH.,
FEMS Microbiol. Letters,
Vol. 138,
179-184.,
1996.
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Nakamura, Y.,
Yamamoto, N.,
Sakai, K.,
Takano, T..
Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme.,
J. Dairy Sci.,
Vol. 78,
1253-1257,
1995.
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Yamamoto, N.,
Akino, A.,
Takano, T.,
Shishido, K..
Presence of active and inactive molecules of a cell wall-associated proteinase in Lactobacillus helveticus CP790.,
Appl. Environ. Microbiol.,
Vol. 61,
698-701,
1995.
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Nakamura, Y.,
Yamamoto, N.,
Sakai, K.,
Okubo, A.,
Yamazaki, S.,
Takano, T..
Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk.,
Vol. 78,
778-783.,
1995.
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Yamamoto, N.,
Akino, A,
Takano, T..
Antihypertensive effect of the peptides derived from casein by an extracellular proteinase from Lactobacillus helveticus CP790.,
J. Dairy Sci.,
Vol. 77,
777-783,
1994.
-
Yamamoto, N.,
Akino, A.,
Takano, T..
Antihypertensive effect of different kinds of fermented milk in spontaneously hypertensive rats.,
Biosci. Biotech. Biochem. 58: 776-778.,
vol. 58,
776-778,
1994.
-
Yamamoto, N.,
Akino, A.,
Takano, T..
Purification and specificity of a cell-wall-associated proteinase from Lactobacillus helveticus CP790,
J. Biochem.,
Vol. 114,
5,
740-745,
Nov. 1993.
著書
-
山本 直之.
乳酸菌発酵乳の血圧降下作用,
腸内細菌の応用と市場,
pp. 91-101,
Feb. 2018.
-
山本 直之.
アレルギー改善乳酸菌の開発,
酵母菌・麹菌・乳案菌の産業応用展開,
シーエムシー出版,
pp. 259-264,
Jan. 2018.
-
山本直之.
Lactobacillus helveticusにおける血圧降下ペプチドの加工,
Agricultural Biotechnology,
Vol. 3,
49-52,
2017.
-
山本直之.
乳酸菌飲料の歴史と製造,
食品産業における発酵と醸造,
印刷中,
2017.
-
山本直之.
血圧降下ペプチドをおいしく摂る,
おいしさの科学的評価・測定法と応用展開,
p. 204-212,
2016.
-
Naoyuki Yamamoto.
Fermented Milks/Health Effects of Fermented Milks,
Encyclopedia of Dairy Science,,
2016.
-
山本直之.
血圧降下作用,
ヨーグルトの事典,
p. 343-348,
2016.
-
山本直之.
血圧降下作用,
p. 258-267,
2013.
-
Yamamoto, N.,
Wakai, T..
Antihypertensive peptides specific to Lactobacillus helveticus fermented milk,
Biotechnology-Molucular Studies and Novel Applications for Improved Quality of Human Life,
p. 159-172,
2012.
-
Naoyuki Yamamoto.
Anti-hypertensive metabolite from lactic acid bacteria,
Lactic Acid Bacteria and Bifidobacteria,
p. 223-232,
2011.
-
山本直之.
乳酸菌・ビフィズス菌の産生する有用物質血圧降下ペプチド,
乳酸菌とビフィズス菌のサイエンス,
p. 333-340,
2010.
-
Naoyuki Yamamoto.
Functional Food products with antihypertensive effects,
Bioactive Proteins and Peptides as Functional Foods and Nutraceuticals,
p. 169-178,
2010.
-
山本直之.
乳酸菌の血圧降下作用,
医科プロバイオティクス学,
p. 425-437,
2008.
-
山本直之.
ラクトトリペプチドの製造,
酵素ハンドブック,
p. 672 678,
2008.
-
山本直之.
乳酸菌における血圧降下ペプチドの生産,
発酵・醸造食品の最新技術と機能性,
p. 226-234.,
2006.
-
山本直之.
乳酸菌飲料の歴史,
発酵乳の科学,
p. 60-66,
2002.
-
Naoyuki Yamamoto.
Health effects of fermented milks,
Encyclopedia of Dairy Science,
pp. 1063-1069,
2002.
-
山本直之.
アミノ酸・ペプチドの取込み,
乳酸菌の科学と技術,
p. 111-116,
1997.
国際会議発表 (査読有り)
-
Yamamoto, N.,
Shinoda, T.,
Takano, T..
Cloning and sequence of an extracellular proteinase gene from Lactobacilus helveticus CP790,
The 6th LAB symposium,
Sept. 1999.
-
Naoyuki Yamamoto,
Yoshiko Masujima,
Toshiaki Takano.
Isolation of an acid-sensitive variant of Lactobacilus helveticus with lower ATPase activity,
The 5th LAB symposium,
Sept. 1996.
-
Naoyuki Yamamoto,
Atsuko Akino,
Toshiaki Takano.
Proteinase activity expression in Lactobacillus helveticus CP790,
The 4th LAB symposium,
Sept. 1993.
国内会議発表 (査読有り)
-
福永もえ,
Chen Xinyue,
梶原将,
山本直之,
折原芳波.
乳由来オピオイドペプチドβ-Casomorphin-10の概日リズムへの影響評価,
日本食品免疫学会学術大会,
Nov. 2023.
-
陳政霖,
宮永一彦,
山本直之.
乳酸菌SlpBを結合したリポソームによる樹状細胞への効率的なドラック・デリバリー・システムの開発,
第38回日本DDS学会学術集会,
June 2022.
-
栗生 識,
山本 直之,
石田 忠.
マウス小腸内部の流体挙動観察を実現するマイクロ流体デバイス開発,
第 38 回「センサ・マイクロマシンと応用システム」シンポジウム,
Nov. 2021.
国際会議発表 (査読なし・不明)
-
Naoyuki Yamamoto.
Advanced knowledge of vascular health in Japan and their successful management,
First International Pan-vascular health forum & New functional food ingredients in vascular health innovation summit,
Nov. 2017.
-
Naoyuki Yamamoto.
Release of antihypertensive peptides, Val-Pro-Pro and Ile-Pro-Pro, in fermented food products,
Oct. 2017.
-
Naoyuki Yamamoto.
Enzymatic Processing and in vivo Actions of Antihypertensive Peptide,
AOCS Annual Meeting,
May 2017.
-
Naoyuki Yamamoto.
Accumulation of ACE inhibitory tripeptides, Val-Pro-Pro and Ile-Pro-Pro into vascular endothelial cells,
5th PepCon Conference,
Mar. 2011.
-
Naoyuki Yamamoto.
Milk derived Tripeptides,
American Society of Hypertension Sympsium,
May 2008.
-
Naoyuki Yamamoto.
Past studies of AmealPeptide,
American Society of Hypertension Symposium,
May 2007.
-
Naoyuki Yamamoto.
Clinical experiences and PK study with AmealPeptide,
International Society of Hypertension Symposium,
Oct. 2006.
-
Naoyuki Yamamoto.
Clinical experiences with AmealPeptide,
American Society of Hypertension Symposium,
May 2006.
-
Naoyuki Yamamoto.
Milk Derived Anti-hypertensive Peptide,
AOSC Symposium,
May 2005.
-
Naoyuki Yamamoto.
Clinical experiences with AmealPeptide,
• Clinical experiences with AmealPeptide,
May 2005.
国内会議発表 (査読なし・不明)
-
栗生識,
山本直之,
石田忠.
絨毛近傍流れ観察のためのマウス小腸組織流路化デバイス開発,
Cheminas 47,
May 2023.
-
山本直之.
乳酸菌による抗アレルギー作用,
微生物研究会,
Nov. 2017.
-
山本直之.
乳酸菌発酵による乳の高付加価値化,
2016年日本酪農科学シンポジウム,
Sept. 2016.
-
山本直之.
機能性ペプチド素材の開発,
第3回SBJシンポジウム,
May 2016.
-
山本直之.
カルピスの開発とその後の技術展開,
日本生物工学会シンポジウム‐第7回生物工学産学技術研究会,
Dec. 2015.
-
山本直之,
中村康則.
乳由来血圧降下ペプチド素材の開発,
農芸化学会関東支部大会,
May 2015.
-
山本直之.
カルピスの開発と販売にまつわる秘話,
第9回日本酪農乳業史研究会 シンポジウム,
Feb. 2015.
-
山本直之.
乳由来血圧降下ペプチドの開発,
日本農芸化学会シンポジウム,
Sept. 2014.
-
山本直之.
腸内細菌と食品,
関東学院大学シンポジウム,
July 2014.
-
山本直之.
乳酸菌における血圧降下ペプチドの生産と制御,
バイオクリニカ,
Vol. 29,
82-86.,
2014.
-
山本直之.
ACE阻害ペプチドLTPの血圧降下作用,
ILSIシンポジウム,
Nov. 2013.
-
山本直之.
乳酸菌の特徴を活かした技術開発,
工業技術会シンポジウム,
Sept. 2013.
-
山本直之.
メタボローム解析を活用した血圧降下素材の開発,
生物工学会シンポジウム,
Mar. 2013.
-
山本直之.
食品由来血圧降下ペプチドの開発と生体への作用,
日本大学薬学部セミナー,
July 2012.
-
山本直之.
血圧とペプチド,
ペプチドシンポジウム,
Oct. 2008.
-
山本直之.
乳酸菌の血圧降下ペプチド,
日大セミナー,
May 2007.
-
山本直之.
乳酸菌の血圧降下作用,
日本乳酸菌学会秋季セミナー,
Dec. 2006.
-
山本直之,
篠田直,
梶山満里子.
Lactobacillus helveticus CM4株ゲノム配列解析からの機能性ペプチド生成メカニズムの解析,
日本生物工学会平成18年度大会シンポジウム,
Sept. 2006.
-
山本直之.
乳酸菌による血圧降下ペプチドの産生,
日本農芸化学会平成18年度大会シンポジウム,
Mar. 2006.
-
山本直之.
乳酸菌の血圧降下ペプチド,
平成17年BFPシンポジウム,
Nov. 2005.
-
水野征一,
西村 新吾,
後藤孝信,
松浦啓一,
山本直之.
カゼインの酵素分解物の血圧降下ペプチドの選択,
日本農芸化学会平成16年度大会,
Mar. 2004.
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松浦啓一,
後藤孝信,
西村新伍,
水野征一,
山本直之.
カゼインの酵素分解物中の血圧降下ペプチドVPPとIPPのLCMSによる定量,
日本農芸化学会平成16年度大会,
Mar. 2004.
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森田英利,
有馬三樹子,
吉川宏,
山本直之,
坂田亮一,
池田輝雄.
Lactobacillus fermentumからの糖鎖結合タンパク質遺伝子のクロー ニング,
日本畜産学会平成12年度大会,
Mar. 2003.
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山本直之.
乳酸菌Lactobacillus helveticus CM4株のエンドペプチダーゼの精製と性質,
日本農芸化学会平成15年度大会,
Mar. 2003.
-
森田英利,
堀川洋,
有馬三樹子,
鈴木武人,
橋爪克仁,
吉川宏,
山本直之,
坂田亮一.
Lactobacillus fermentumからの糖鎖結合タンパク質遺伝子のクロー ニング,
ヒト腸管糖鎖結合性のLactobacillus fermentum由来蛋白質遺伝子の欠損株の作出,
Mar. 2003.
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中村太志,
石田優,
板東出樹,
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山本直之.
Lactobacillus acidophilus L92株の経口投与がマウス血清中の卵白アルブミン特異的IgE抗体レベルに及ぼす影響,
日本農芸化学会平成15年度大会,
Mar. 2003.
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山本直之.
血圧降下ペプチド生産における乳酸菌の可能性,
日本農芸化学会平成14年度大会シンポジウム,
Mar. 2002.
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山本直之.
乳酸菌発酵乳の保健効果に期待すること,
麻布大学市民大学セミナー,
Aug. 2000.
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森田英利,
有馬三樹子,
山本直之.
乳酸菌の腸管接着因子のクローニングとシーケンス,
July 2000.
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山本直之,
有馬三樹子.
病原性大腸菌の腸管接着性因子fimHの乳酸菌での発現の試み,
July 2000.
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山本直之.
乳酸菌Lactobacillus helveticusCP790菌体外プロティナーゼ遺伝子のクローニングとシーケンス,
日本農芸化学会平成12年度大会,
Apr. 2000.
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有馬三樹子,
森田英利,
山本直之,
篠田直,
池田輝男,
坂田亮一.
大腸菌由来ヒト腸管付着性タンパク質(fimH)遺伝子のグラム陽性菌での発現の試み,
日本畜産学会平成12年度大会,
Mar. 2000.
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有馬三樹子,
森田英利,
山本直之,
篠田直,
池田輝雄,
坂田亮一.
大腸菌由来ヒト腸管付着性タンパク質(fimH)遺伝子のグラム陽性菌での発現の試み,
日本畜産学会平成12年度大会,
2000.
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山本直之.
血圧降下ペプチド開発の可能性と課題,
日本乳酸菌学会セミナー平成11年度大会シンポジウム,
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山本直之.
発酵乳内の血圧降下ペプチド,
日本酪農科学会平成11年度大会,
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山本直之.
発酵乳由来の血圧降下ペプチド,
日本酪農科学会シンポジウム,
1999.
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山本直之.
Lactobacillus helveticus発酵ヨーグルト内の血圧降下ペプチドの精製とその性質,
日本農芸化学会平成10年度大会,
Mar. 1998.
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山本直之,
増島佳子,
高野俊明.
Lactobacillus helveticusの酸感受性変異菌の分離とその性質,
日本農芸化学会平成7年度大会,
Aug. 1995.
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山本直之,
増島佳子,
高野俊明.
Lactobacillus helveticusの酸感受性変異菌の分離とその性質,
乳酸菌研究集談会平成7年度大会,
June 1995.
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山本直之.
Lactobacillus helveticusの菌体外プロティナーゼのカゼイン分解ペプチドの血圧降下作用,
日本生化学会平成6年度大会,
Apr. 1994.
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山本直之.
Lactobacillus helveticusのプロティナーゼについて,
• 乳酸菌研究集談会1992年度大会,
June 1992.
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山本直之,
坂間厚子,
高野俊明.
Lactobacillus helveticusの菌体外プロティナーゼの活性発現機構の検討,
日本農芸化学会平成4年度大会,
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坂間厚子,
山本直之,
高野俊明.
Lactobacillus helveticusの菌体外プロティナーゼの精製及びモノクローナル抗体の作製,
日本農芸化学会平成4年度大会,
Mar. 1992.
その他の論文・著書など
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山本直之.
アレルギー改善乳酸菌の開発,
酵母菌・麹菌・乳酸菌の産業応用展開,
Vol. 8,
52,
17,
Dec. 2017.
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山本直之.
乳酸菌による抗アレルギー作用,
Medical Science Digest,
Vol. 43,
33-37.,
2017.
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Naoyuki Yamamoto.
Value added milk by lactic acid bacteria fermentation.,
Milk Science,
Vol. 65,
211-217.,
2016.
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山本直之.
Lactobacillus helveticusにおける血圧降下ペプチドの加工,
アレルギーの臨床,
1092-1095.,
2016.
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山本直之.
Lactobacillus helveticusにおける血圧降下ペプチドの加工,
細胞,
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32-35.,
2015.
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山本直之.
乳由来血圧降下素材の開発,
化学と生物,
Vol. 53,
619-625.,
2015.
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山本直之.
カルピスの開発と販売にまつわる秘話,
酪農乳業史研究,
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11-14.,
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山本直之.
腸内細菌と食品開発,
GI Research,
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50-55.,
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山本直之.
乳酸菌における血圧降下ペプチドの生産,
Foods & Food Ingredients Journal of Japan,
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774-779.,
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Naoyuki Yamamoto.
Antihypertensive peptides from food proteins.,
Research Trends,
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Naoyuki Yamamoto,
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Biogenic peptides and their potential use.,
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山本直之.
乳酸菌の発酵により生産される血圧降下ペプチド,
日本農芸化学会誌,
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2002.
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山本直之.
乳酸菌と血圧降下ぺプチド,
バイオクリニカ,
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263-267.,
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山本直之.
血圧降下ペプチド開発の可能性と課題,
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Vol. 10,
142-145.,
2000.
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山本直之.
乳酸菌と血圧降下作用,
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血圧降下ペプチド産生に関与する乳酸菌蛋白質分解酵素系,
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